This work investigates whether the application of sonoporation is limited by the size of a
macromolecule being delivered and by the ability of cells to proliferate following uptake …

This work investigates the effect of ultrasound exposure parameters on the sonoporation of
KHT-C cells in suspension by perflutren microbubbles. Variations in insonating acoustic …

Ultrasound-induced microbubble destruction can enhance drug delivery to cells. The
molecular weight of therapeutic compounds varies significantly (from< 1 kDa for small …

Ultrasound insonation of microbubbles can be used to form pores in cell membranes and
facilitate the local trans-membrane transport of drugs and genes. An important factor in …

For sonoporation to be established as a drug/gene delivery paradigm, it is essential to
account for the biological impact of this membrane permeation strategy on living cells. Here …

Cell sonoporation enables the delivery of various exogenous molecules into the cells. To
maximize the percentage of reversibly sonoporated cells and to increase cell viability we …

Ultrasound-induced intracellular drug delivery, sonoporation, is an appealing and promising
technique for next generation drug delivery system. Many types of molecules, such as …

Ultrasound application in the presence of microbubbles is a promising strategy for
intracellular drug and gene delivery, but it may also trigger other cellular responses. This …

Microbubbles (MBs) have been shown to create transient or lethal pores in cell membranes
under the influence of ultrasound, known as ultrasound-mediated sonoporation. Several …

Sonoporation is a useful biophysical mechanism for facilitating the transmembrane delivery
of therapeutic agents from the extracellular to the intracellular milieu. Conventionally …