Background Janus kinase (JAK) inhibitors are emerging as a promising new treatment
modality for many inflammatory conditions. Objective Our aim was to systematically review …

Background Janus kinase (JAK) inhibitors have attracted attention for their role in treating
inflammatory disorders. This new class of biologics has the potential to significantly affect the …

Janus kinase inhibitors, also commonly referred to as JAK inhibitors, are a novel drug class
that target and block cytokine signaling mediated by the Janus kinase-signal transducer and …

The Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway
is a ubiquitous intracellular signaling network. Selective JAK-inhibitors have anti …

Introduction Numerous cutaneous dermatoses mediated by cytokines depend on the JAK
STAT pathway for intracellular signaling. JAK inhibitors form a useful therapeutic approach …

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular
signaling pathway is implicated in the pathogenesis of a number of inflammatory …

Objectives To evaluate the efficacy and safety of Janus kinase (JAK) inhibitors (Jakinibs) in
the treatment of psoriasis and psoriatic arthritis (PsA). Methods Databases including …

Atopic dermatitis (AD) is a chronic heterogeneous condition characterized by erythematous,
pruritic, and inflamed skin. Janus kinase (JAK) inhibitors are a new class of drugs that target …

The Janus kinase-signal transducer and activator of transcription (JAK-STAT) intracellular
signaling pathway is utilized by many proinflammatory molecules to mediate downstream …

Janus kinases inhibitors are molecules that target Janus kinases—signal transducers and
activators of transcription (JAK/STAT). They inhibit this intracellular signal pathway, blocking …