An update on the roles of circular RNAs in osteosarcoma

Z Li, X Li, D Xu, X Chen, S Li, L Zhang… - Cell …, 2021 - Wiley Online Library
Osteosarcoma is the most common primary bone malignancy and is a neoplasm thought to
be derived from the bone‐forming mesenchymal stem cells. Aberrant activation of …

[HTML][HTML] The regulatory functions of circular RNAs in osteosarcoma

N Soghli, D Qujeq, T Yousefi, N Soghli - Genomics, 2020 - Elsevier
Osteosarcoma (OS) is known as a malignant bone tumor affecting mainly children and
younger adults. Despite all the improvements in the treatment of OS, the overall survival …

[HTML][HTML] The roles of circular RNAs in osteosarcoma

Y Zhang, J Li, Y Wang, J Jing, J Li - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
Osteosarcoma is a malignant tumor that occurs most commonly in the metaphysis of the long
bones in the limbs in children and adolescents. Even with surgery and neoadjuvant …

[HTML][HTML] Circular RNA hsa_circ_0000073 contributes to osteosarcoma cell proliferation, migration, invasion and methotrexate resistance by sponging miR-145-5p and …

X Li, Y Liu, X Zhang, J Shen, R Xu, Y Liu, X Yu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
An increasing number of studies have demonstrated that circular RNAs (circRNAs), as
promising therapeutic targets, are essential for diverse human diseases, especially cancer …

Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression

Y Wu, Z Xie, J Chen, J Chen, W Ni, Y Ma, K Huang… - Molecular cancer, 2019 - Springer
Background As a subclass of noncoding RNAs, circular RNAs (circRNAs) have been
demonstrated to play a critical role in regulating gene expression in eukaryotes. Recent …

Circular RNA hsa_circ_0001564 regulates osteosarcoma proliferation and apoptosis by acting miRNA sponge

YZ Song, JF Li - Biochemical and biophysical research communications, 2018 - Elsevier
Circular RNAs (circRNAs) is a novel type of non-coding RNAs generated from back splicing,
which has been verified to mediate multiple tumorigenesis. However, the role of circRNA in …

Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis

B Yang, L Li, G Tong, Z Zeng, J Tan, Z Su, Z Liu… - Journal of Experimental …, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) are involved in diverse processes that drive
cancer development. However, the expression landscape and mechanistic function of …

[HTML][HTML] Upregulation of circular RNA circ_0001721 predicts unfavorable prognosis in osteosarcoma and facilitates cell progression via sponging miR-569 and miR …

L Li, L Guo, G Yin, G Yu, Y Zhao, Y Pan - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Osteosarcoma (OS) is the most frequent bone malignancy in human. Growing evidence
suggests that circular RNAs (circRNAs) play a significant role in regulating tumorigenesis …

[HTML][HTML] Circular RNA hsa-circ-0016347 promotes proliferation, invasion and metastasis of osteosarcoma cells

H Jin, X Jin, H Zhang, W Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a novel class of non-coding RNA which have recently shown
huge capabilities in the regulation of gene expression at the post-transcriptional level …

[HTML][HTML] Microarray expression profile and functional analysis of circular RNAs in osteosarcoma

W Liu, J Zhang, C Zou, X Xie, Y Wang… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Osteosarcoma (OS) is the most common primary malignant bone tumor in
children and adolescents. However, the molecular mechanisms regulating osteosarcoma …