Natural killer cells: a promising immunotherapy for cancer

J Chu, F Gao, M Yan, S Zhao, Z Yan, B Shi… - Journal of translational …, 2022 - Springer
As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

Harnessing natural killer cell antitumor immunity: from the bench to bedside

KV Woan, JS Miller - Cancer immunology research, 2019 - AACR
Natural killer (NK) cells are critical effector lymphocytes mediating tumor immune
surveillance and clearance. They do so by direct tumor killing using cytolytic granules and …

The NK cell–cancer cycle: advances and new challenges in NK cell–based immunotherapies

T Bald, MF Krummel, MJ Smyth, KC Barry - Nature immunology, 2020 - nature.com
Natural killer (NK) cells belong to the innate immune system and contribute to protecting the
host through killing of infected, foreign, stressed or transformed cells. Additionally, via …

Natural killer cell immunotherapy for cancer: a new hope

S Srivastava, A Lundqvist, RW Childs - Cytotherapy, 2008 - Elsevier
Recently there has been a substantial gain in our understanding of the role NK-cells play in
mediating innate host immune responses. Although NK cells have long been known to …

Natural killer cells: a review of biology, therapeutic potential and challenges in treatment of solid tumors

K Choucair, JR Duff, CS Cassidy, MT Albrethsen… - Future …, 2019 - Taylor & Francis
Natural killer (NK) cells lead immune surveillance against cancer and early elimination of
small tumors. Owing to their ability to engage tumor targets without the need of specific …

Natural killer cells in antitumour adoptive cell immunotherapy

TJ Laskowski, A Biederstädt, K Rezvani - Nature Reviews Cancer, 2022 - nature.com
Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with
intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing …

NK cells and cancer: you can teach innate cells new tricks

MG Morvan, LL Lanier - Nature Reviews Cancer, 2016 - nature.com
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review …

Prospects for the use of NK cells in immunotherapy of human cancer

HG Ljunggren, KJ Malmberg - Nature Reviews Immunology, 2007 - nature.com
Current insights into the molecular specificities that regulate natural killer (NK)-cell function
suggest that it might be possible to design NK-cell-based immunotherapeutic strategies …

NK cells to cure cancer

C Di Vito, J Mikulak, E Zaghi, S Pesce… - Seminars in …, 2019 - Elsevier
Natural Killer (NK) cells are innate lymphocytes able to mediate immune-surveillance and
clearance of viral infected and tumor-transformed cells. Growing experimental and clinical …

Bringing natural killer cells to the clinic: ex vivo manipulation

RW Childs, M Berg - Hematology 2013, the American Society …, 2013 - ashpublications.org
Recently, there has been a substantial gain in our understanding of the role that natural
killer (NK) cells play in mediating innate host immune responses against viruses and cancer …