The efficacy and safety of direct oral anticoagulants vs traditional anticoagulants in cirrhosis

J Hum, JJ Shatzel, JH Jou… - European journal of …, 2017 - Wiley Online Library
Introduction The coagulopathy of cirrhosis is complex, placing patients at risk for both
bleeding and thrombosis. Direct oral anticoagulants (DOAC s) have equivalent or superior …

Direct oral anticoagulants in cirrhosis patients pose similar risks of bleeding when compared to traditional anticoagulation

NM Intagliata, ZH Henry, H Maitland, NL Shah… - Digestive diseases and …, 2016 - Springer
Abstract Background and Aims Direct oral anticoagulants (DOAC) are important new
anticoagulant therapies that are not well studied in patients with chronic liver disease. The …

Direct oral anticoagulants in patients with liver cirrhosis: a systematic review

EW Hoolwerf, N Kraaijpoel, HR Büller, N Van Es - Thrombosis research, 2018 - Elsevier
Introduction Anticoagulant treatment in patients with liver cirrhosis is challenging. The aim of
this systematic review was to evaluate clinical outcomes of direct oral anticoagulant (DOAC) …

Direct oral anticoagulants in cirrhotic patients: current evidence and clinical observations

S Elhosseiny, H Al Moussawi… - Canadian Journal of …, 2019 - Wiley Online Library
The introduction of Direct Oral Anticoagulants (DOACs) to the pharmaceutical market
provided patients and clinicians with novel convenient and safe options of anticoagulation …

Direct oral anticoagulants in cirrhosis

NM Intagliata, H Maitland, SH Caldwell - Current treatment options in …, 2016 - Springer
Opinion statement The risk of thrombosis in patients with chronic liver disease is
increasingly recognized. As patients with cirrhosis develop indications for anticoagulation …

Rates of bleeding and discontinuation of direct oral anticoagulants in patients with decompensated cirrhosis

JF Mort, JPE Davis, G Mahoro, MJ Stotts… - Clinical …, 2021 - Elsevier
Background & Aims Studies of the effects of direct oral anticoagulants (DOACs) in patients
with cirrhosis have been limited by their small sample size, inclusion of patients with well …

Direct oral anticoagulants and advanced liver disease: a systematic review and meta‐analysis

D Menichelli, V Ronca, A Di Rocco… - European Journal of …, 2021 - Wiley Online Library
Abstract Background Direct oral anticoagulants (DOACs) are recommended for stroke
prevention in patients with atrial fibrillation (AF) or for treatment of deep vein thrombosis …

Direct oral anticoagulants in chronic liver disease

TD Steuber, ML Howard… - Annals of …, 2019 - journals.sagepub.com
Objective: To review the use of direct oral anticoagulants (DOACs) in patients with chronic
liver disease (CLD). Data Sources: A MEDLINE literature search was performed from 1964 …

Direct-acting oral anticoagulants (DOACs) in cirrhosis and cirrhosis-associated portal vein thrombosis

EM Weinberg, J Palecki… - Seminars in Liver Disease, 2019 - thieme-connect.com
Direct-acting oral anticoagulants (DOACs) have provided benefit in patients requiring
anticoagulation for certain diseases by decreasing the burden of subcutaneous injections …

Safety of direct oral anticoagulants vs warfarin in patients with chronic liver disease and atrial fibrillation

P Goriacko, KT Veltri - European journal of haematology, 2018 - Wiley Online Library
Background A complication of chronic liver disease (CLD) is the abnormality of coagulation.
In clinical practice, this increased risk of bleeding has not been identified as a protective …