Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

Causal genes and variants within genome-wide association study (GWAS) loci can be
identified by integrating GWAS statistics with expression quantitative trait loci (eQTL) and …

Transcriptomic imputation approaches combine eQTL reference panels with large-scale
genotype data in order to test associations between disease and gene expression. These …

Schizophrenia is a highly heritable mental disorder characterized by functional
dysconnectivity across the brain. However, the relationships between polygenic risk factors …

Background While schizophrenia differs between males and females in the age of onset,
symptomatology, and disease course, the molecular mechanisms underlying these …

Background The importance of cell type-specific epigenetic variation of non-coding regions
in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are …

Schizophrenia is a severe, complex mental disorder characterized by a combination of
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

Importance Schizophrenia (SCZ) is a devastating psychiatric condition. Identifying the
specific genetic variants and pathways that increase susceptibility to SCZ is critical to …

Psychiatry is undergoing a paradigm shift from the acceptance of distinct diagnoses to a
representation of psychiatric illness that crosses diagnostic boundaries. How this transition …