Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

Psychiatric disorders such as schizophrenia, bipolar disorder, major depressive disorder,
attention-deficit/hyperactivity disorder and autism spectrum disorder are common and result …

Importance Schizophrenia is a complex heritable disorder associated with many genetic
variants, each with a small effect. While cortical differences between patients with …

Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and
function differ, on average, between people with schizophrenia and healthy individuals. As …

Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …

Family study results are consistent with genetic effects making substantial contributions to
risk of psychiatric disorders such as schizophrenia, yet robust identification of specific …

Despite large-scale genome-wide association studies (GWAS), the underlying genes for
schizophrenia are largely unknown. Additional approaches are therefore required to identify …

The application of microarray technology in schizophrenia research was heralded as
paradigm-shifting, as it allowed for high-throughput assessment of cell and tissue function …

Genes disrupted in schizophrenia may be revealed by de novo mutations in affected
persons from otherwise healthy families. Furthermore, during normal brain development …