R Martinez-Monedero, K Oshima, S Heller, ASB Edge - Hearing research, 2007 - Elsevier
Stem cells in various mammalian organs retain the capacity to renew themselves and may be able to restore damaged tissue. Their existence has been proven by genetic tracer …
K Oshima, P Senn, S Heller - Auditory and Vestibular Research: Methods …, 2009 - Springer
The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either …
In this review, we compared the potential of mesenchymal stem cells derived from bone marrow, adipose tissue and umbilical cord as suitable sources for regeneration of inner ear …
The presence of stem cells in the organ of Corti raises the hope of regeneration of mammalian inner ear cells. However, little is known about the distribution of endogenous …
R Martinez-Monedero, ASB Edge - International Journal of …, 2007 - researchgate.net
Stem cells in the nervous system have some capacity to restore damaged tissue. Proliferation of stem cells endows them with self-renewal ability and accounts for in vitro …
T Okano, MW Kelley - Trends in amplification, 2012 - journals.sagepub.com
In vertebrates, perception of sound, motion, and balance is mediated through mechanosensory hair cells located within the inner ear. In mammals, hair cells are only …
S Kanzaki, M Toyoda, A Umezawa… - International journal of …, 2020 - mdpi.com
Inner and middle ear disorders are the leading cause of hearing loss, and are said to be among the greatest risk factors of dementia. The use of regenerative medicine for the …
P Senn, A Mina, S Volkenstein… - The Anatomical …, 2020 - Wiley Online Library
Loss of inner ear hair cells leads to incurable balance and hearing disorders because these sensory cells do not effectively regenerate in humans. A potential starting point for therapy …
S Dazert, C Aletsee, D Brors, H Sudhoff… - DNA and cell …, 2003 - liebertpub.com
The use of stem cells offers new and powerful strategies for future tissue development and engineering. Common features of stem cells are both their capacity for self-renewal and the …