[PDF][PDF] Endogenous Stem Cells in the Ear

KH Park - Korean J Otorhinolaryngol-Head Neck Surg, 2013 - Citeseer
Basically stem cells have characteristics of multi-potency, differentiation into multiple tissue
types, and self-renew through proliferation. Recent advances in stem cell biology can make …

The potential role of endogenous stem cells in regeneration of the inner ear

R Martinez-Monedero, K Oshima, S Heller, ASB Edge - Hearing research, 2007 - Elsevier
Stem cells in various mammalian organs retain the capacity to renew themselves and may
be able to restore damaged tissue. Their existence has been proven by genetic tracer …

Isolation of sphere-forming stem cells from the mouse inner ear

K Oshima, P Senn, S Heller - Auditory and Vestibular Research: Methods …, 2009 - Springer
The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This
deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either …

[HTML][HTML] Comparison of three types of mesenchymal stem cells (bone marrow, adipose tissue, and umbilical cord-derived) as potential sources for inner ear …

MR Mahmoudian-Sani… - The International …, 2017 - tinnitusjournal.com
In this review, we compared the potential of mesenchymal stem cells derived from bone
marrow, adipose tissue and umbilical cord as suitable sources for regeneration of inner ear …

Comparison of sphere-forming capabilities of the cochlear stem cells derived from apical, middle and basal turns of murine organ of Corti

X Lou, J Xie, X Wang, L Yang, Y Zhang - Neuroscience Letters, 2014 - Elsevier
The presence of stem cells in the organ of Corti raises the hope of regeneration of
mammalian inner ear cells. However, little is known about the distribution of endogenous …

[PDF][PDF] Stem cells for the replacement of inner ear neurons and hair cells

R Martinez-Monedero, ASB Edge - International Journal of …, 2007 - researchgate.net
Stem cells in the nervous system have some capacity to restore damaged tissue.
Proliferation of stem cells endows them with self-renewal ability and accounts for in vitro …

Stem cell therapy for the inner ear: recent advances and future directions

T Okano, MW Kelley - Trends in amplification, 2012 - journals.sagepub.com
In vertebrates, perception of sound, motion, and balance is mediated through
mechanosensory hair cells located within the inner ear. In mammals, hair cells are only …

Application of mesenchymal stem cell therapy and inner ear regeneration for hearing loss: a review

S Kanzaki, M Toyoda, A Umezawa… - International journal of …, 2020 - mdpi.com
Inner and middle ear disorders are the leading cause of hearing loss, and are said to be
among the greatest risk factors of dementia. The use of regenerative medicine for the …

Progenitor cells from the adult human inner ear

P Senn, A Mina, S Volkenstein… - The Anatomical …, 2020 - Wiley Online Library
Loss of inner ear hair cells leads to incurable balance and hearing disorders because these
sensory cells do not effectively regenerate in humans. A potential starting point for therapy …

Regeneration of inner ear cells from stem cell precursors—a future concept of hearing rehabilitation?

S Dazert, C Aletsee, D Brors, H Sudhoff… - DNA and cell …, 2003 - liebertpub.com
The use of stem cells offers new and powerful strategies for future tissue development and
engineering. Common features of stem cells are both their capacity for self-renewal and the …