Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …

The role of oxidative stress in the initiation and progress of epilepsy is well established.
Proanthocyanidins (PACs), a naturally occurring polyphenolic compound, have been …

Evidence points towards oxidative stress and neuroinflammation being major processes
associated with brain dysfunction in epilepsy. Salidroside reportedly possesses anti …

Background Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor, which
activates the anti-oxidative stress response pathway. In epilepsy, oxidative stress is one of …

Objective Role of apoptosis and neuroinflammation have been well established in the
pathogenesis of epilepsy. It has been reported that the activation of nuclear factor-erythroid …

Background Epilepsy is one of the major neurological disorders. The inflammatory process
and oxidative stress are closely related to seizure progression. Quercetin is a flavonoid with …

Epilepsy is a chronic disease of the brain that affects over 65 million people worldwide.
Acquired epilepsy is initiated by neurological insults, such as status epilepticus, which can …

Background: Oxidative stress plays a key role in the pathogenesis of epilepsy and
contributes in underlying epileptogenesis process. Anticonvulsant drugs targeting the …

Most antiepileptic drugs (AEDs) interfere with cognitive function, and there is therefore an
urgent need for AEDs that are effective but do not have this side effect. Various studies have …

Background Epilepsy is a severe neurological disorder associated with substantial morbidity
and mortality. Vanillin (Van) is a natural phenolic aldehyde with beneficial pharmacological …