The prevalence of neurodegenerative disease has increased significantly in recent years,
and with a rapidly aging global population, this trend is expected to continue. These …

Neurodegenerative diseases are neuronal disorders characterized by the loss of a large
number of neurons in the human brain. Innate immunity-mediated neuroinflammation …

In an ageing society, neurodegenerative diseases have attracted attention because of their
high incidence worldwide. Despite extensive research, there is a lack of conclusive insights …

Inflammasomes are supramolecular protein complexes implicated in the detection of
pathogens or danger-associated molecules and are responsible for mounting the first line of …

Neurodegenerative diseases are characterized by a dysregulated neuro-glial
microenvironment, culminating in functional deficits resulting from neuronal cell death …

Central nervous system (CNS) is one of the largest killers of people's health all over the
world. The overactivation of the immune and inflammatory responses is considered as an …

The NLRP3 inflammasome is a multimeric protein complex that initiates an inflammatory
form of cell death and triggers the release of proinflammatory cytokines IL-1β and IL-18. The …

Inflammasomes are intracellular multiprotein complexes in the cytoplasm that regulate
inflammation activation in the innate immune system in response to pathogens and to host …

Neuroinflammatory response is the immune response mechanism of the innate immune
system of the central nervous system. Both primary and secondary injury can activate …

Neurodegenerative diseases are chronic, progressive disorders that occur in the central
nervous system (CNS). They are characterized by the loss of neuronal structure and function …