The doubly labeled water (DLW) method was developed 50 years ago, but nearly 40 years
passed before it became a major tool for human nutrition research. Its use has grown …

Scientists have been measuring energy expenditure by using gas exchange for the past 200
y. This technique is based on earlier work in the 1660s. Gas exchange in respirometers …

Obesity is defined as the excess storage of energy in the form of fat that results from
imbalances between energy intake and expenditure. The study of the components of energy …

The doubly labeled water (DLW) method is considered the reference method for the
measurement of energy expenditure under free-living conditions. However, the …

Objective: To evaluate whether the doubly labeled water (DLW) method is precise under
conditions required for a large-scale evaluation of dietary intake instruments. Design …

The turnover rates of water and carbon dioxide have been estimated at frequent intervals
after a single dose of 2H2 18O had been given to an adult monitored continuously in a …

The doubly labelled water method for the assessment of energy expenditure was first
published in 1955, application in humans started in 1982, and it has become the gold …

The accuracy and noninvasive nature of the doubly labeled water (DLW) method makes it
ideal for the study of human energy metabolism in free-living conditions. However, the DLW …

The doubly labelled water method for estimating total energy expenditure in free-living
persons is reviewed. The method has enabled researchers to demonstrate that adaptive …

The doubly labeled water (2H2 (18) O) method to assess energy expenditure in free-living
conditions has been successfully validated against gas exchange measurements in lean …