Deep learning supported discovery of biomarkers for clinical prognosis of liver cancer

J Liang, W Zhang, J Yang, M Wu, Q Dai, H Yin… - Nature Machine …, 2023 - nature.com
Tissue biomarkers are crucial for cancer diagnosis, prognosis assessment and treatment
planning. However, there are few known biomarkers that are robust enough to show true …

Development of AI-based pathology biomarkers in gastrointestinal and liver cancer

JN Kather, J Calderaro - Nature Reviews Gastroenterology & …, 2020 - nature.com
Deep learning can mine clinically useful information from histology. In gastrointestinal and
liver cancer, such algorithms can predict survival and molecular alterations. Once pathology …

[HTML][HTML] Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer …

A Bakrania, N Joshi, X Zhao, G Zheng, M Bhat - Pharmacological research, 2023 - Elsevier
Liver cancers are the fourth leading cause of cancer-related mortality worldwide. In the past
decade, breakthroughs in the field of artificial intelligence (AI) have inspired development of …

PAGE-Net: interpretable and integrative deep learning for survival analysis using histopathological images and genomic data

J Hao, SC Kosaraju, NZ Tsaku, DH Song… - Pacific Symposium on …, 2019 - World Scientific
The integration of multi-modal data, such as histopathological images and genomic data, is
essential for understanding cancer heterogeneity and complexity for personalized …

Artificial Intelligence-Based Opportunities in Liver Pathology—A Systematic Review

P Allaume, N Rabilloud, B Turlin, E Bardou-Jacquet… - Diagnostics, 2023 - mdpi.com
Background: Artificial Intelligence (AI)-based Deep Neural Networks (DNNs) can handle a
wide range of applications in image analysis, ranging from automated segmentation to …

Regression-based Deep-Learning predicts molecular biomarkers from pathology slides

OSM El Nahhas, CML Loeffler, ZI Carrero… - nature …, 2024 - nature.com
Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically
approved applications use this technology. Most approaches, however, predict categorical …

Deep learning in cancer pathology: a new generation of clinical biomarkers

A Echle, NT Rindtorff, TJ Brinker, T Luedde… - British journal of …, 2021 - nature.com
Clinical workflows in oncology rely on predictive and prognostic molecular biomarkers.
However, the growing number of these complex biomarkers tends to increase the cost and …

Deep learning in cancer diagnosis and prognosis prediction: a minireview on challenges, recent trends, and future directions

AB Tufail, YK Ma, MKA Kaabar… - … Methods in Medicine, 2021 - Wiley Online Library
Deep learning (DL) is a branch of machine learning and artificial intelligence that has been
applied to many areas in different domains such as health care and drug design. Cancer …

Interpretable survival prediction for colorectal cancer using deep learning

E Wulczyn, DF Steiner, M Moran, M Plass, R Reihs… - NPJ digital …, 2021 - nature.com
Deriving interpretable prognostic features from deep-learning-based prognostic
histopathology models remains a challenge. In this study, we developed a deep learning …

A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images

S Arslan, J Schmidt, C Bass, D Mehrotra… - Communications …, 2024 - nature.com
Background The objective of this comprehensive pan-cancer study is to evaluate the
potential of deep learning (DL) for molecular profiling of multi-omic biomarkers directly from …