Serum interleukin-6 is an indicator for severity in 901 patients with SARS-CoV-2 infection: a cohort study

J Zhang, Y Hao, W Ou, F Ming, G Liang, Y Qian… - Journal of translational …, 2020 - Springer
Abstract Background Interleukin-6 (IL-6) was proposed to be associated with the severity of
coronavirus disease 2019 (COVID-19). The present study aimed to explore the kinetics of IL …

Blood interferon-α levels and severity, outcomes, and inflammatory profiles in hospitalized COVID-19 patients

M Contoli, A Papi, L Tomassetti, P Rizzo… - Frontiers in …, 2021 - frontiersin.org
Background: Deficient interferon responses have been proposed as one of the relevant
mechanisms prompting severe manifestations of COVID-19. Objective: To evaluate the …

Dynamic interleukin-6 level changes as a prognostic indicator in patients with COVID-19

Z Liu, J Li, D Chen, R Gao, W Zeng, S Chen… - Frontiers in …, 2020 - frontiersin.org
Background Interleukin-6 (IL-6), a proinflammatory cytokine, has been reported to be
associated with disease severity and mortality in patients with coronavirus disease 2019 …

[HTML][HTML] Elevated interleukin‐6 is associated with severity of COVID‐19: a meta‐analysis

J Zhu, J Pang, P Ji, Z Zhong, H Li, B Li… - Journal of medical …, 2021 - ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID‐19) has spread rapidly around the world since its
emergence in humans last December. Previous studies suggested that numerous markers …

[HTML][HTML] Interleukin-6 as a potential biomarker of COVID-19 progression

ZS Ulhaq, GV Soraya - Medecine et maladies infectieuses, 2020 - ncbi.nlm.nih.gov
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),
alsoknownasthe2019novelCoronavirus (2019-nCoV), has caused a recent outbreak of …

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis

JX Yin, YL Agbana, ZS Sun, SW Fei, HQ Zhao… - Infectious Diseases of …, 2023 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) can involve persistence,
sequelae, and other clinical complications that last weeks to months to evolve into long …

Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis

J Gorham, A Moreau, F Corazza, L Peluso… - PLoS …, 2020 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) appeared in China in December 2019
and has spread around the world. High Interleukin-6 (IL-6) levels in COVID-19 patients …

Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

[PDF][PDF] IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

Serial measurement of cytokines strongly predict COVID-19 outcome

HS Ozger, R Karakus, EN Kuscu, UE Bagriacik… - PloS one, 2021 - journals.plos.org
Purpose Cytokines are major mediators of COVID-19 pathogenesis and several of them are
already being regarded as predictive markers for the clinical course and outcome of COVID …