Over the past three decades, the number of people globally with diabetes mellitus has more
than doubled. It is estimated that by 2030, 439 million people will be suffering from the …

Background: Genome-wide polygenic risk scores (PRS) have shown high specificity and
sensitivity in predicting type 2 diabetes (T2D) risk in Europeans. However, the PRS-driven …

Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic
and environmental risk factors that disproportionately afflicts communities of color …

Numerous type 2 diabetes (T2D) polygenic risk scores (PGSs) have been developed to
predict individuals' predisposition to the disease. An independent assessment and …

ABSTRACT Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and
environmental risk factors that disproportionately afflicts communities of color. Leveraging …

One of the major challenges in the post-genomic era is elucidating the genetic basis of
human diseases. In recent years, studies have shown that polygenic risk scores (PRS) …

Type 2 diabetes (T2D) with increasing prevalence is a significant global public health
challenge. Obesity, unhealthy diet, and low physical activity are one of the major …

Polygenic risk score (PRS) has been shown to be predictive of disease risk such as type 2
diabetes (T2D). However, the existing studies on genetic prediction for T2D only had limited …

Genome-wide polygenic risk scores (PRS) for lifestyle disorders, like Type 2 Diabetes (T2D),
are useful in identifying at-risk individuals early on in life, and to guide them towards …

With the rise in the prevalence of type 2 diabetes (T2D), as well as undiagnosed cases of
T2D and prediabetes (25% and 90%, respectively), early detection is imperative to minimize …