Maternal immune activation in neurodevelopmental disorders

CM Solek, N Farooqi, M Verly, TK Lim… - Developmental …, 2018 - Wiley Online Library
Converging lines of evidence from basic science and clinical studies suggest a relationship
between maternal immune activation (MIA) and neurodevelopmental disorders such as …

Controversies and prospects about microglia in maternal immune activation models for neurodevelopmental disorders

S Smolders, T Notter, SMT Smolders, JM Rigo… - Brain, behavior, and …, 2018 - Elsevier
Activation of the maternal immune system during pregnancy is a well-established risk factor
for neuropsychiatric disease in the offspring, yet, the underlying mechanisms leading to …

Maternal immune activation: Implications for neuropsychiatric disorders

ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …

[HTML][HTML] Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the …

RM Woods, JM Lorusso, HG Potter, JC Neill… - Neuroscience & …, 2021 - Elsevier
Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

[HTML][HTML] Virus-induced maternal immune activation as an environmental factor in the etiology of autism and schizophrenia

A Massrali, D Adhya, DP Srivastava… - Frontiers in …, 2022 - frontiersin.org
Maternal immune activation (MIA) is mediated by activation of inflammatory pathways
resulting in increased levels of cytokines and chemokines that cross the placental and blood …

[HTML][HTML] Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

Prenatal maternal immune activation and brain development with relevance to psychiatric disorders

G Scola, A Duong - Neuroscience, 2017 - Elsevier
Growing evidence from epidemiological studies strongly suggests maternal infection as a
risk factor for psychiatric disorders including bipolar disorder, schizophrenia, and autism …

The role of maternal immune activation in altering the neurodevelopmental trajectories of offspring: A translational review of neuroimaging studies with implications for …

E Guma, E Plitman, MM Chakravarty - Neuroscience & Biobehavioral …, 2019 - Elsevier
Exposure to maternal infection in utero increases the risk that offspring will develop
neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia …

[HTML][HTML] Maternal immune activation and related factors in the risk of offspring psychiatric disorders

F Conway, AS Brown - Frontiers in psychiatry, 2019 - frontiersin.org
Maternal immune activation (MIA) at the time of gestation has been linked to increased risk
of neurodevelopmental psychiatric disorders. Animal and human models have been used to …

[HTML][HTML] Maternal immune activation induces sustained changes in fetal microglia motility

K Ozaki, D Kato, A Ikegami, A Hashimoto, S Sugio… - Scientific reports, 2020 - nature.com
Maternal infection or inflammation causes abnormalities in brain development associated
with subsequent cognitive impairment and in an increased susceptibility to schizophrenia …