Abstract Absence of Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein,
is responsible for the Fragile X syndrome, the most common form of inherited mental …

We have performed mRNA in situ hybridization studies and northern blot analysis in the
mouse and human, respectively, to determine the normal gene expression patterns of FMR …

Expansion of a trinucleotide (CGG) repeat element within the 5′ untranslated region (5′
UTR) of the human FMR1 gene is responsible for a number of heritable disorders operating …

Fragile X syndrome, an X-linked dominant disorder with reduced penetrance, is associated
with intellectual and emotional disabilities ranging from learning problems to mental …

The absence of the fragile X mental retardation protein (FMRP), encoded by the FMR1 gene,
is responsible for pathologic manifestations in the Fragile X Syndrome, the most frequent …

Abstract Fragile X Syndrome (FXS) is the most common form of inherited intellectual
disability due to the silencing of the FMR1 gene encoding FMRP (Fragile X Mental …

The Fragile X syndrome, which results from the absence of functional FMRP protein, is the
most common heritable form of mental retardation. Here, we show that FMRP acts as a …

The fragile X mental retardation 1 gene (FMR 1)‐related disorder fragile X syndrome (FXS)
is the most common heritable form of cognitive impairment and the second most common …

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is due to
the functional deficiency of the fragile X mental retardation protein (FMRP), an RNA-binding …

Fragile X syndrome (FXS) is a common form of inherited intellectual disability and is one of
the leading known causes of autism. The mutation responsible for FXS is a large expansion …