“Good Fashion is Evolution, Not Revolution”-Methods to Enhance Existing Anticancer Medicines, Primarily with the Use of Transition Metal

M Guzowska, M Kalinowska… - Anti-Cancer Agents in …, 2018 - ingentaconnect.com
The constant search for successful cancer therapies lasts for decades. Apart from the huge
scientific effort and enormous sum of spent money, only a small amount of newly developed …

Editorial [Hot topic: Metal-Containing Drugs and Novel Coordination Complexes in Therapeutic Anticancer Applications-Part II (Guest Editor: Irena Kostova)]

I Kostova - Anti-Cancer Agents in Medicinal Chemistry …, 2010 - ingentaconnect.com
While cancer remains a major killer in the developed world, a broad spectrum of novel and
exciting approaches are being developed and tested. The importance of metal compounds …

The role of metals in the next generation of anticancer therapeutics

JJ Wilson, TC Johnstone - Current Opinion in Chemical Biology, 2023 - Elsevier
Conclusion We very much appreciated working with all the authors noted above on
assembling this special issue and we hope that you enjoy reading their excellent …

Metal anticancer complexes–activity, mechanism of action, future perspectives

E Alessio, Z Guo - European journal of inorganic chemistry, 2017 - Wiley Online Library
Guest editors Enzo Alessio and Zijian Guo present an overview of the topics reported in the
papers of this issue, listing the general trends that dominate the field of metal anticancer …

Metallodrugs in cancer therapy: past, present and new strategies

I Kostova - Frontiers in Chemistry, 2024 - frontiersin.org
Cancer diagnostics and therapy that include metal-based pharmaceuticals have improved
over the past decades. The therapeutic importance and application of metals and their …

Metal complexes in cancer therapy–an update from drug design perspective

U Ndagi, N Mhlongo, ME Soliman - Drug design, development and …, 2017 - Taylor & Francis
In the past, metal-based compounds were widely used in the treatment of disease
conditions, but the lack of clear distinction between the therapeutic and toxic doses was a …

New trends for metal complexes with anticancer activity

PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …

A survey of the mechanisms of action of anticancer transition metal complexes

M Marloye, G Berger, M Gelbcke… - Future medicinal …, 2016 - Taylor & Francis
Metal complexes have been the subject of numerous investigations in oncology but, despite
the plethora of newly synthesized compounds, their precise mechanisms of action remain …

Metal complexes of natural product like-compounds with antitumor activity

BL Heras, Á Amesty, A Estévez-Braun… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Cancer continues to be one of the major causes of death worldwide. Despite many
advances in the understanding of this complex disease, new approaches are needed to …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …