Weathering the cytokine storm in susceptible patients with severe SARS-CoV-2 infection
High-risk patients requiring hospitalization for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection are those over 60 years old, males, obese, smokers …
coronavirus 2 (SARS-CoV-2) infection are those over 60 years old, males, obese, smokers …
SARS-CoV-2 triggering autoimmune diseases
L Mobasheri, MH Nasirpour, E Masoumi… - Cytokine, 2022 - Elsevier
Autoimmunity, hyperstimulation of the immune system, can be caused by a variety of
reasons. Viruses are thought to be important environmental elements that contribute to the …
reasons. Viruses are thought to be important environmental elements that contribute to the …
[HTML][HTML] Monocytes and macrophages in severe COVID‐19–friend, foe or both?
While most COVID-19 patients have mild symptoms, about 15% of patients develop severe
COVID-19 often with fatal outcomes, and scientists have been on the hunt to understand the …
COVID-19 often with fatal outcomes, and scientists have been on the hunt to understand the …
[PDF][PDF] Innate immunity in COVID-19: Drivers of pathogenesis and potential therapeutic targets
V Ruenjaiman, N Hirankarn… - Asian Pacific journal of …, 2021 - apjai-journal.org
A novel severe acute respiratory syndrome COVID-19 caused by coronavirus SARS-CoV-2
has been confirmed to infect more than 100 million people globally, with mortality reaching …
has been confirmed to infect more than 100 million people globally, with mortality reaching …
[HTML][HTML] Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …
to acute respiratory distress syndrome and death. Three highly pathogenic human …
Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases
Beyond the acute illness caused by severe acute respiratory coronavirus 2 (SARS-CoV-2)
infection, about one-fifth of infections result in long-term persistence of symptoms despite the …
infection, about one-fifth of infections result in long-term persistence of symptoms despite the …
The immunology and immunopathology of COVID-19
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …
[HTML][HTML] Preexisting comorbidities shape the immune response associated with severe COVID-19
S Kreutmair, M Kauffmann, S Unger… - Journal of Allergy and …, 2022 - Elsevier
Background Comorbidities are risk factors for development of severe coronavirus disease
2019 (COVID-19). However, the extent to which an underlying comorbidity influences the …
2019 (COVID-19). However, the extent to which an underlying comorbidity influences the …
COVID-19: an immunopathological view
K Kadkhoda - MSphere, 2020 - Am Soc Microbiol
Since its emergence in December 2019, it took only a couple of months for an outbreak of
the novel coronavirus disease 2019 (COVID-19) to be declared a pandemic by the World …
the novel coronavirus disease 2019 (COVID-19) to be declared a pandemic by the World …
The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity
IG Ovsyannikova, IH Haralambieva… - Immunological …, 2020 - Wiley Online Library
This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …