[HTML][HTML] A vicious cycle: in severe and critically Ill COVID-19 patients

P Huang, Q Zuo, Y Li, PK Oduro, F Tan… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, is one of the fastest-evolving viral diseases …

The Role of Inflammatory Cytokines (Interleukin-1 and Interleukin-6) as a Potential Biomarker in the Different Stages of COVID-19 (Mild, Severe, and Critical)

M Ghofrani Nezhad, G Jami, O Kooshkaki… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokine storm refers to the overproduction of immune and inflammatory cells and their
proteins (cytokines)[interleukin (IL)-1 and IL-6] causing acute respiratory distress syndrome …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
The newfound coronavirus disease 2019 (COVID-19), initiated by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an international public health concern …

[HTML][HTML] Cytokines from bench to bedside: A retrospective study identifies a definite panel of biomarkers to early assess the risk of negative outcome in COVID-19 …

M Fabris, F Del Ben, E Sozio, AP Beltrami… - International Journal of …, 2022 - mdpi.com
The main aim of this study was to identify the most relevant cytokines which, when assessed
in the earliest stages from hospital admission, may help to select COVID-19 patients with …

The immune system and COVID-19: Friend or foe?

F Yazdanpanah, MR Hamblin, N Rezaei - Life sciences, 2020 - Elsevier
Abstract Aim Coronavirus disease 2019 (COVID-19) is a novel highly contagious infection
caused by SARS-CoV-2, which has been became a global public health challenge. The …

[HTML][HTML] Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[HTML][HTML] COVID-19 is a multifaceted challenging pandemic which needs urgent public health interventions

C Contini, E Caselli, F Martini, M Maritati, E Torreggiani… - Microorganisms, 2020 - mdpi.com
Until less than two decades ago, all known human coronaviruses (CoV) caused diseases so
mild that they did not stimulate further advanced CoV research. In 2002 and following years …

[HTML][HTML] Immune Response and COVID-19: A mirror image of Sepsis

E Lopez-Collazo, J Avendano-Ortiz… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 virus and its associated disease COVID-19 have triggered
significant threats to public health, in addition to political and social changes. An important …