Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery

C Feng, J Shi, Q Fan, Y Wang, H Huang, F Chen… - Nature …, 2021 - nature.com
SARS-CoV-2 vaccination has been launched worldwide to build effective population-level
immunity to curb the spread of this virus. The effectiveness and duration of protective …

SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

J Wu, B Liang, C Chen, H Wang, Y Fang… - Nature …, 2021 - nature.com
Long-term antibody responses and neutralizing activities in response to SARS-CoV-2
infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies …

Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination

G Mantus, LE Nyhoff, VV Edara, VI Zarnitsyna… - Cell Reports …, 2022 - cell.com
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
highlights the importance of determining the breadth and durability of humoral immunity to …

Will SARS-CoV-2 infection elicit long-lasting protective or sterilising immunity? Implications for vaccine strategies (2020)

DS Kim, S Rowland-Jones… - Frontiers in …, 2020 - frontiersin.org
In December 2019, an outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China
resulted in the current COVID-19 global pandemic. The human immune system has not …

Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents

N Koerber, A Priller, S Yazici, T Bauer… - Nature …, 2022 - nature.com
Anti-viral immunity continuously declines over time after SARS-CoV-2 infection. Here, we
characterize the dynamics of anti-viral immunity during long-term follow-up and after …

Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection

J Zuo, AC Dowell, H Pearce, K Verma, HM Long… - Nature …, 2021 - nature.com
The immune response to SARS-CoV-2 is critical in controlling disease, but there is concern
that waning immunity may predispose to reinfection. We analyzed the magnitude and …

Inflammation, immunity, and antigen persistence in post-acute sequelae of SARS-CoV-2 infection

KL Newell, AT Waickman - Current Opinion in Immunology, 2022 - Elsevier
Highlights•Post-acute sequelae of SARS-CoV-2 (PASC) are associated with persistent
inflammation.•The antigens or other immune stimuli driving PASC are still unclear.•PASC …

Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset

SP Anand, J Prévost, M Nayrac… - Cell Reports …, 2021 - cell.com
With the recent approval of highly effective coronavirus disease 2019 (COVID-19) vaccines,
functional and lasting immunity to severe acute respiratory syndrome coronavirus 2 (SARS …

Lasting antibody and T cell responses to SARS-CoV-2 in COVID-19 patients three months after infection

XL Jiang, GL Wang, XN Zhao, FH Yan, L Yao… - Nature …, 2021 - nature.com
The dynamics, duration, and nature of immunity produced during SARS-CoV-2 infection are
still unclear. Here, we longitudinally measured virus-neutralising antibody, specific …

SARS-CoV-2-specific CD4+ T cells are associated with long-term persistence of neutralizing antibodies

Z Wang, X Yang, X Mei, Y Zhou, Z Tang, G Li… - … and Targeted Therapy, 2022 - nature.com
Understanding the decay and maintenance of long-term SARS-CoV-2 neutralizing
antibodies in infected or vaccinated people and how vaccines protect against other SARS …