To explore the hypothesis that alterations in ethanolamine plasmalogen may be directly
related to the severity of dementia in Alzheimer's disease (AD), we performed a systematic …

J. Neurochem.(2011) 116, 916–925. Abstract Lipids play an important role as risk or
protective factors in Alzheimer's disease, which is characterized by amyloid plaques …

Background: Plasmalogens, which are key structural phospholipids in brain membranes, are
decreased in the brain and serum of patients with Alzheimer disease (AD). We performed …

Although dementia of the Alzheimer's type (DAT) is the most common form of dementia, the
severity of dementia is only weakly correlated with DAT pathology. In contrast, postmortem …

ObjectiveWe undertook a non-targeted lipidomics analysis of post-mortem cerebrospinal
fluid (CSF), frontal cortex grey matter, and subjacent white matter to define potential …

A significant and selective deficiency of ethanolamine plasmalogen (PPE) relative to
phosphatidylethanolamine was identified in post mortem brain samples from patients with …

Growing evidence suggests that ethanolamine plasmalogens (PlsEtns), a subtype of
phospholipids, have a close association with Alzheimer's disease (AD). Decreased levels of …

The normal stability of the cell membrane bilayer depends on its lipid composition being
appropriate to the ambient (physiological) temperature, Tp. Membrane lipid composition …

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD).
Previously it has been shown that plasmalogens, the major brain phospholipids, are altered …

Abstract Background Plasmalogens (Pls) reportedly decreased in postmortem brain and in
the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal …