This review examines key pharmacological strategies that have been clinically studied for
the primary or secondary prevention of Alzheimer's disease. Much information …

Alzheimer's disease (AD) is the major cause of late-life brain failure. In the past 25 years,
autosomal dominant forms of AD were found to be primariy attributable to mutations in one …

The prevention of Alzheimer disease (AD) remains an important goal because of its high
prevalence in our society and its associated costs. Two types of primary prevention trials …

Alzheimer's disease is an ever-increasing health concern among the aging population, and
as we research new and existing treatments for this disease we begin to uncover …

Despite enormous financial and scientific efforts, still no approved disease-modifying
therapies exist for Alzheimer's disease (AD). During the last decade all Phase III clinical …

A growing body of evidence suggests that several classes of drugs marketed for other
indications may be effective in the prevention of Alzheimer's disease. Among the most …

Alzheimer's disease (AD) is the leading cause of dementia, presenting a significant unmet
medical need worldwide. The pathogenesis of AD involves various pathophysiological …

Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …

While advances have been made in understanding the neurobiological processes
underlying Alzheimer's disease (AD), few treatment options currently exist. Numerous …

Background: Alzheimer's disease (AD) is the most common cause of cognitive impairment in
older patients and is expected to increase greatly in prevalence. Interventions that could …