The gut microbiota plays a major role in the developmental biology and homeostasis of cells
belonging to the adaptive and innate arms of the immune system. Alterations in its …

The immune system is essential for maintaining a delicate balance between eliminating
pathogens and maintaining tolerance to self‐tissues to avoid autoimmunity. An enormous …

Autoimmune diseases have long been known to share a common pathogenesis involving a
dysregulated immune system with a failure to recognize self from non-self-antigens. This …

To maintain health, the immune system must maintain a delicate balance between
eliminating invading pathogens and avoiding immune disorders such as autoimmunity and …

Keeping a delicate balance in the immune system by eliminating invading pathogens, while
still maintaining self-tolerance to avoid autoimmunity, is critical for the body's health. The gut …

The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …

The composition of a host's intestinal microbiota directs the type of mucosal and systemic
immune responses by affecting the proportion and number of functionally distinct T cell …

Trillions of microbes survive and thrive inside the human body. These tiny creatures are
crucial to the development and maturation of our immune system and to maintain gut …

Immunological dysregulation is the cause of many non-infectious human diseases such as
autoimmunity, allergy and cancer. The gastrointestinal tract is the primary site of interaction …