On the basis of epidemiological studies, a low high-density lipoprotein cholesterol (HDL-C)
level is considered as an independent risk factor for the development of cardiovascular …

Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Despite a robust inverse association between high-density lipoprotein (HDL) cholesterol
levels and atherosclerotic cardiovascular disease, the development of new therapies based …

Lipoproteins are endogenously present nanocarriers and are the primary commuters of
cholesterol within the body. Among lipoproteins, HDL inherits size in nm range with anti …

El objetivo de mi tesis se centra en el desarrollo de partículas recombinantes que imitan las
pre-ßHDL naturales, para su utilización como medio de transporte de microRNAs. Estas …

High Density Lipoproteins (HDLs) have long been considered as “good cholesterol,”
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …

High-density lipoproteins (HDLs) are among the most structurally complex and functionally
versatile forms of circulating serum lipoproteins. HDLs undergo extensive enzymatic …

The ability of HDL to support macrophage cholesterol efflux is an integral part of its
atheroprotective action. Augmenting this ability, especially when HDL cholesterol efflux …

Increasing evidence has cast doubt over the HDL-cholesterol hypothesis. The complexity of
the HDL particle and its proven susceptibility to remodel has paved the way for intense …

High-density lipoprotein (HDL) serves as a natural nanoparticle with compositional and
functional heterogeneity and contributes to the maintenance of lipid metabolism and various …