[HTML][HTML] Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

[HTML][HTML] Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

A Mazzoni, L Salvati, L Maggi… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Coronavirus disease 19 (COVID-19) is an emerging infectious disease
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen …

[HTML][HTML] COVID-19: towards understanding of pathogenesis

W Cao, T Li - Cell research, 2020 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) is spreading rapidly. Although the
cause was quickly identified as a new coronavirus named SARS-CoV-2, our knowledge of …

[HTML][HTML] Cellular immune response to COVID-19 and potential immune modulators

X Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

[HTML][HTML] Immunological and inflammatory profiles in mild and severe cases of COVID-19

JW Song, C Zhang, X Fan, FP Meng, Z Xu, P Xia… - Nature …, 2020 - nature.com
Abstract COVID-19 is associated with 5.1% mortality. Although the virological,
epidemiological, clinical, and management outcome features of COVID-19 patients have …

T‐cell responses and therapies against SARS‐CoV‐2 infection

SM Toor, R Saleh, V Sasidharan Nair, RZ Taha… - …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2, a novel
coronavirus strain. Some studies suggest that COVID‐19 could be an immune‐related …

COVID-19: an immunopathological view

K Kadkhoda - MSphere, 2020 - Am Soc Microbiol
Since its emergence in December 2019, it took only a couple of months for an outbreak of
the novel coronavirus disease 2019 (COVID-19) to be declared a pandemic by the World …