The holistic approach of personalized medicine, merging clinical and molecular
characteristics to tailor the diagnostic and therapeutic path to each individual, is steadily …

Background Treatment in bipolar disorder (BD) is commonly applied as a multimodal
therapy based on decision algorithms that lack an integrative understanding of molecular …

The hopes for readily implementable precision medicine are high. For many complex
disorders, such as bipolar disorder, these hopes critically hinge on tangible successes in …

Bipolar disorder (BD) is a lifelong severe psychiatric condition with high morbidity, disability
and excess mortality. The longitudinal clinical trajectory of BD is significantly modified by …

Bipolar disorder (BD) is a chronic and often severe psychiatric illness characterized by
manic and depressive episodes. Among the most effective treatments, mood stabilizers …

This is a personal perspective on bipolar disorder, entirely written by a well-informed patient
who is a successful mental heath professional. The patient prefers to remain anonymous; …

Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …

Realizing the promise of precision medicine in psychiatry is a laudable and beneficial
endeavor, since it should markedly reduce morbidity and mortality and, in effect, alleviate the …

Several pharmacogenetic-based decision support tools for psychoactive medication
selection are available. However, the scientific evidence of the gene-drug pairs analyzed is …

Bipolar disorder (BD) is a common and disabling psychiatric condition with a severe
socioeconomic impact. BD is treated with mood stabilizers, among which lithium represents …