[HTML][HTML] Precision psychiatry applications with pharmacogenomics: artificial intelligence and machine learning approaches
A growing body of evidence now suggests that precision psychiatry, an interdisciplinary field
of psychiatry, precision medicine, and pharmacogenomics, serves as an indispensable …
of psychiatry, precision medicine, and pharmacogenomics, serves as an indispensable …
The search for personalized antidepressant treatments: what have we learned and where are we going
A Serretti, C Fabbri - Pharmacogenomics, 2020 - Future Medicine
Over 20 years after the initial report of gene variants within the central nervous system
modulating antidepressant response, we are now facing for the first time routine clinical …
modulating antidepressant response, we are now facing for the first time routine clinical …
[图书][B] Genetic influences on response to drug treatment for major psychiatric disorders
JK Rybakowski, A Serretti - 2016 - Springer
Psychiatric disorders affect a significant percentage of the population, making the issue of
their optimal treatment an extremely important one. A judicious use of pharmacological …
their optimal treatment an extremely important one. A judicious use of pharmacological …
Combining genetic and genomic approaches to study mood disorders
Recent technological advances in genetic manipulations and DNA microarrays are
profoundly altering the landscape of biological research, offering opportunities to investigate …
profoundly altering the landscape of biological research, offering opportunities to investigate …
[HTML][HTML] Integrated proteomic and genomic analysis to identify predictive biomarkers for valproate response in bipolar disorder: a 6-month follow-up study
Background Several genetic studies have been undertaken to elucidate the intricate
interplay between genetics and drug responses in bipolar disorder (BD). However, there has …
interplay between genetics and drug responses in bipolar disorder (BD). However, there has …
Pharmacogenomics in Psychiatric Diseases
A Kekic - Pharmacogenomics in Clinical Practice, 2024 - Springer
Mental health disorders are prevalent, complex, and difficult to treat illnesses.
Psychopharmacotherapy is the cornerstone of their treatment. Drug selection is still heuristic …
Psychopharmacotherapy is the cornerstone of their treatment. Drug selection is still heuristic …
Pharmacogenomics of psychiatric drug treatment.
D Mancama, MJ Arranz, RW Kerwin - Current Opinion in Molecular …, 2003 - europepmc.org
Clinical outcome to psychiatric drug therapy varies widely among patients. A significant
proportion fail to respond satisfactorily, while others react adversely to these compounds …
proportion fail to respond satisfactorily, while others react adversely to these compounds …
Genetics of long-term treatment outcome in bipolar disorder
C Fabbri, A Serretti - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Bipolar disorder (BD) shows one of the strongest genetic predispositions among psychiatric
disorders and the identification of reliable genetic predictors of treatment response could …
disorders and the identification of reliable genetic predictors of treatment response could …
[图书][B] Psychiatric Genomics
Psychiatric Genomics presents and synthesizes available knowledge in the field of
psychiatric genomics, offering methodologies to advance new research and aid clinical …
psychiatric genomics, offering methodologies to advance new research and aid clinical …
Evaluation of potential novel variations and their interactions related to bipolar disorders: analysis of genome-wide association study data
C Acikel, Y Aydin Son, C Celik, H Gul - … disease and treatment, 2016 - Taylor & Francis
Background Multifactor dimensionality reduction (MDR) is a nonparametric approach that
can be used to detect relevant interactions between single-nucleotide polymorphisms …
can be used to detect relevant interactions between single-nucleotide polymorphisms …