Adverse drug reactions (ADRs) are noxious and unexpected effects during normal drug
therapy. They have caused significant clinical burden and been responsible for a large …

Adverse drug events (ADEs) occur when multiple drugs interact within an individual, thus
causing effects that were not initially predicted. Such toxic interactions lead to morbidity and …

A standardized, controlled vocabulary allows adverse drug events (ADE) information to be
described in an unambiguous way in knowledge bases, which is critical for clinical decision …

Despite of their therapeutic effects, drug's exposure may have negative effects on human
health such as adverse drug reaction (ADR) and side effects (SE). Adverse drug events …

Abstract Background Adverse drug reactions (ADRs) are one of the leading causes of
morbidity and mortality in health care. Understanding which drug targets are linked to ADRs …

Background Accurate prediction of adverse drug events (ADEs) is an important means of
controlling and reducing drug-related morbidity and mortality. Since no single “gold …

Background Studies of toxicity and unintended side effects can lead to improved drug safety
and efficacy. One promising form of study comes from molecular systems biology in the form …

Surveillance of pharmacovigilance, also known as drug safety surveillance, involves the
monitoring and evaluation of drug-related adverse events or side effects to ensure the safe …

Explainable AI (XAI) is a methodology that complements the black box of artificial
intelligence, and its necessity has recently been highlighted in various fields. The purpose of …

OBJECTIVE: The purpose of this study was to integrate knowledge about drugs, drug
targets, and topological methods. The goals were to build a system facilitating the study of …