Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation

A Corsonello, C Pedone, F Lattanzio, G Onder… - Drugs & aging, 2011 - Springer
Background: Reduced renal function increases the risk of adverse drug reactions (ADRs) to
hydrosoluble drugs (hADRs). However, the ability of different equations to calculate …

Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients

A Corsonello, C Pedone, F Corica… - Archives of internal …, 2005 - jamanetwork.com
Background Adverse drug reactions (ADRs) are common causes of in-hospital
complications for elderly people. The purpose of the present study is to verify whether …

Estimating renal function to reduce the risk of adverse drug reactions

A Corsonello, G Onder, S Bustacchini, M Provinciali… - Drug safety, 2012 - Springer
The aging process is characterized by relevant changes in pharmacokinetics. Renal function
is known to decline with aging. However, as a result of reduced muscle mass, older …

Survivability of hospitalized chronic kidney disease (CKD) patients with moderate to severe estimated glomerular filtration rate (eGFR) after experiencing adverse drug …

M Danial, MA Hassali, LM Ong, AH Khan - BMC Pharmacology and …, 2018 - Springer
Background Accurate identification and routine preventive practices are crucial steps in
lessening the incidence of medications and patients related adverse drug reactions (ADRs) …

Adverse drug reactions in older patients during hospitalisation: are they predictable?

MN O'connor, P Gallagher, S Byrne… - Age and …, 2012 - academic.oup.com
Background: adverse drug reactions (ADRs) are a major cause of morbidity and healthcare
utilisation in older people. The GerontoNet ADR risk score aims to identify older people at …

Adverse drug reactions and impaired renal function in elderly patients admitted to the emergency department: a retrospective study

A Helldén, U Bergman, M von Euler, M Hentschke… - Drugs & aging, 2009 - Springer
Abstract Background Adverse drug reactions (ADRs) are common in elderly patients. There
are various reasons for this, including age-and disease-related alterations in …

Concealed renal failure and adverse drug reactions in older patients with type 2 diabetes mellitus

A Corsonello, C Pedone, F Corica… - The Journals of …, 2005 - academic.oup.com
Background. In elderly patients serum creatinine may be normal despite decreased
glomerular filtration rate (GFR). The aim of this study was to evaluate the prevalence of this …

[HTML][HTML] Kidney function decline and serious adverse drug reactions in patients with CKD

SM Laville, V Gras-Champel, A Hamroun… - American Journal of …, 2024 - Elsevier
Rationale & Objective Adverse drug reactions (ADRs) are common in patients with chronic
kidney disease (CKD). The impact of kidney function decline on serious ADR risk has been …

Inappropriate drug use and mortality in community-dwelling elderly with impaired kidney function—the Three-City population-based study

G Breton, M Froissart, N Janus… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Glomerular filtration rate (GFR) decline with age increases the risk of
inappropriate dosing of drugs. We investigated the determinants and the mortality …

Clinical value of automatic reporting of estimated glomerular filtration rate in geriatrics

H Kurtal, V Schwenger, M Azzaro, N Abdollahnia… - Gerontology, 2009 - karger.com
Background: Geriatric patients frequently have impaired renal function. Multimorbidity leads
to polypharmacy with high risk of adverse drug reactions. Objective: The aim was to evaluate …