Microglia are rapidly activated following ischaemic stroke and participate in the induction of
neuroinflammation, which exacerbates the injury of ischaemic stroke. However, the …

The mechanisms underlying neuroinflammation following cerebral ischemia remain unclear.
Hydrogen sulfide (H 2 S), a newly identified gasotransmitter, has been reported to regulate …

Background Tissue damage and cellular destruction are the major events in traumatic brain
injury (TBI), which trigger sterile neuroimmune and neuroinflammatory responses in the …

Neuroinflammation contributes to the pathogenesis of early brain injury (EBI) after
subarachnoid hemorrhage (SAH). Cytotoxic events following SAH, such as extracellular …

Hemorrhagic transformation (HT) is a complication of severe ischemic stroke after
revascularization. Patients with low platelet counts do not receive reperfusion therapies due …

The biological function of interleukin‐10 (IL‐10) and the relationship between IL‐10
secretion and the Toll‐like receptor 2 (TLR 2) expression levels in the central nervous …

The c-Jun-N-terminal kinase signaling pathway (JNK) is highly activated during ischemia
and plays an important role in apoptosis and inflammation. We have previously …

Background Emerging studies have demonstrated the important physiological and
pathophysiological roles of hydrogen sulphide (H 2 S) as a gasotransmitter for NOD-like …

Neuroinflammation occurs after germinal matrix hemorrhage (GMH) and induces secondary
brain injury. Interferon-α (IFN-α) has been shown to exert anti-inflammatory effects in …

Objective The aims of the present study were to detect the interaction of Wip1 and NF-κB
P65 in retina of an LPS-induced astrocytes activation model. Methods The interaction …