Dopamine and extinction: a convergence of theory with fear and reward circuitry

AD Abraham, KA Neve, KM Lattal - Neurobiology of learning and memory, 2014 - Elsevier
Research on dopamine lies at the intersection of sophisticated theoretical and
neurobiological approaches to learning and memory. Dopamine has been shown to be …

Activation of D1/5 dopamine receptors: a common mechanism for enhancing extinction of fear and reward-seeking behaviors

AD Abraham, KA Neve, KM Lattal - Neuropsychopharmacology, 2016 - nature.com
Dopamine is critical for many processes that drive learning and memory, including
motivation, prediction error, incentive salience, memory consolidation, and response output …

Insights into the role of dopamine receptor systems in learning and memory

M El-Ghundi, BF O'Dowd, SR George - Reviews in the …, 2007 - degruyter.com
Insights into the Role of Dopamine Receptor Systems in Learning and Memory Page 1 ©
Freund & Pettman, UK Reviews in the Neurosciences, 18, 37-66 (2007) Insights into the Role …

A dopaminergic basis for fear extinction

R Kalisch, AMV Gerlicher, S Duvarci - Trends in cognitive sciences, 2019 - cell.com
It is a joyous relief when an event we dread fails to materialize. In fear extinction, the
appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the …

Dopamine, learning and motivation

RA Wise - Nature reviews neuroscience, 2004 - nature.com
The hypothesis that dopamine is important for reward has been proposed in a number of
forms, each of which has been challenged. Normally, rewarding stimuli such as food, water …

Dopamine: from prediction error to psychotherapy

S Papalini, T Beckers, B Vervliet - Translational psychiatry, 2020 - nature.com
Dopamine, one of the main neurotransmitters in the mammalian brain, has been implicated
in the coding of prediction errors that govern reward learning as well as fear extinction …

Dopamine in fear extinction

XI Salinas-Hernández, S Duvarci - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
The ability to extinguish fear memories when threats are no longer present is critical for
adaptive behavior. Fear extinction represents a new learning process that eventually leads …

The cognitive neuroscience of motivation and learning

ND Daw, D Shohamy - Social Cognition, 2008 - Guilford Press
Recent advances in the cognitive neuroscience of motivation and learning have
demonstrated a critical role for midbrain dopamine and its targets in reward prediction …

A dopaminergic switch for fear to safety transitions

R Luo, A Uematsu, A Weitemier, L Aquili… - Nature …, 2018 - nature.com
Overcoming aversive emotional memories requires neural systems that detect when fear
responses are no longer appropriate so that they can be extinguished. The midbrain ventral …

Tripartite mechanism of extinction suggested by dopamine neuron activity and temporal difference model

WX Pan, R Schmidt, JR Wickens… - Journal of …, 2008 - Soc Neuroscience
Extinction of behavior enables adaptation to a changing world and is crucial for recovery
from disorders such as phobias and drug addiction. However, the brain mechanisms …