[PDF][PDF] The effect of coronaviruses on olfaction: systematic review

M Zugaj, NS van Ditzhuijzen, K Golebski, WJ Fokkens - Rhinology, 2021 - researchgate.net
Background: Unlike other respiratory viruses, SARS-CoV-2 causes anosmia without
sinonasal inflammation. Here we systematically review the effects of the 7 known human …

Mechanisms of SARS-CoV-2-associated anosmia

T Tsukahara, DH Brann, SR Datta - Physiological Reviews, 2023 - journals.physiology.org
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …

Background mechanisms of olfactory dysfunction in COVID-19: expression of ACE2, TMPRSS2, and Furin in the nose and olfactory bulb in human and mice

R Ueha, K Kondo, R Kagoya, S Shichino, S Ueha… - BioRxiv, 2020 - biorxiv.org
Background Anosmia is a frequent symptom in patients with the coronavirus disease 2019
(COVID-19) driven by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and …

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

DH Brann, T Tsukahara, C Weinreb, M Lipovsek… - Science …, 2020 - science.org
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …

[HTML][HTML] Pathophysiology of SARS-CoV-2 infection of nasal respiratory and olfactory epithelia and its clinical impact

J Chee, B Chern, WS Loh, J Mullol… - Current Allergy and Asthma …, 2023 - Springer
Abstract Purpose of Review While the predominant cause for morbidity and mortality with
SARS‐CoV‐2 infection is the lower respiratory tract manifestations of the disease, the effects …

Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms

R Butowt, K Bilinska, CS von Bartheld - Trends in Neurosciences, 2023 - cell.com
The mechanisms of olfactory dysfunction in COVID-19 are still unclear. In this review, we
examine potential mechanisms that may explain why the sense of smell is lost or altered …

COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

GD De Melo, F Lazarini, S Levallois… - Science translational …, 2021 - science.org
Whereas recent investigations have revealed viral, inflammatory, and vascular factors
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …

Olfactory dysfunction as a post-infectious symptom of SARS-CoV-2 infection

BA Othman, SQ Maulud, PJ Jalal… - Annals of Medicine …, 2022 - journals.lww.com
The unexpected onset smell and taste disability was being recognized as a COVID-19
related symptom. Loss of smell might occur alone or be followed by other COVID-19 …

Is SARS‐CoV‐2 (COVID‐19) postviral olfactory dysfunction (PVOD) different from other PVOD?

SA Imam, WP Lao, P Reddy, SA Nguyen… - World Journal of …, 2020 - Wiley Online Library
Background The SARS‐CoV‐2 virus continues to spread rapidly across the globe afflicting
many with Coronavirus Disease 2019 (COVID‐19). As the infection rates rise, a growing …

[HTML][HTML] Pathogenesis of olfactory disorders in COVID-19

L Ziuzia-Januszewska, M Januszewski - Brain sciences, 2022 - mdpi.com
Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as
a frequent symptom of COVID-19; however, its pathogenesis is still debated. The aim of this …