B-type natriuretic peptide at early reperfusion limits infarct size in the rat isolated heart

DS Burley, GF Baxter - Basic research in cardiology, 2007 - Springer
Natriuretic peptides are regulatory autacoids in the mammalian myocardium whose
functions, mediated via particulate guanylyl cyclase/cGMP, may include cytoprotection …

B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening

SP D'souza, DM Yellon, C Martin… - American Journal …, 2003 - journals.physiology.org
B-type natriuretic peptide (BNP) has been reported to be released from the myocardium
during ischemia. We hypothesized that BNP mediates cardioprotection during ischemia …

Natriuretic peptides and myocardial ischaemia

GF Baxter - Basic research in cardiology, 2004 - Springer
In both experimental and clinical myocardial ischaemia, release of BNP occurs rapidly from
ventricular myocardium, prompting speculation that the early activation of the natriuretic …

Pretreatment with B-type natriuretic peptide protects the heart from ischemia-reperfusion injury by inhibiting myocardial apoptosis

B Wu, H Jiang, R Lin, B Cui, H Wen… - The Tohoku journal of …, 2009 - jstage.jst.go.jp
The therapy for acute myocardial infarction (AMI) has been improved; yet, AMI remains a
major cause of death and heart failure in industrialized countries. B-type natriuretic peptide …

Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts

XM Yang, S Philipp, JM Downey, MV Cohen - Basic research in cardiology, 2006 - Springer
We investigated whether atrial natriuretic peptide (ANP) given just prior to reperfusion
reduces infarction in rabbit hearts and whether protection is related to activation of protein …

B-type natriuretic peptide infusions in acute myocardial infarction

RJ Hillock, CM Frampton, TG Yandle, RW Troughton… - Heart, 2008 - heart.bmj.com
Background: Natriuretic peptides have actions likely to ameliorate cardiac dysfunction. B-
type natriuretic peptide (BNP) is indicated as treatment for decompensated cardiac failure …

Clinical significance of acute-phase brain natriuretic peptide in acute myocardial infarction treated with direct coronary angioplasty.

T Katayama, H Nakashima, T Yonekura… - Journal of …, 2003 - europepmc.org
Objectives To investigate the relationship between brain natriuretic peptide (BNP) plasma
concentration levels and the clinical course, mortality and success of left ventricular …

Atrial natriuretic peptide protects against ischemia-reperfusion injury in the isolated rat heart

K Sangawa, K Nakanishi, K Ishino, M Inoue… - The Annals of thoracic …, 2004 - Elsevier
BACKGROUND: Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate
cyclase, has been found to protect against reoxygenation-induced hypercontracture in …

Brain natriuretic peptide limits myocardial infarct size dependent of nitric oxide synthase in rats

B Ren, Y Shen, H Shao, J Qian, H Wu, H Jing - Clinica Chimica Acta, 2007 - Elsevier
BACKGROUND: Brain natriuretic peptide (BNP) has recently been shown to have a
cardioprotective effect in animal models of myocardial ischemia-reperfusion (IR) injury. We …

Rapid ventricular induction of brain natriuretic peptide gene expression in experimental acute myocardial infarction

N Hama, H Itoh, G Shirakami, O Nakagawa, S Suga… - Circulation, 1995 - Am Heart Assoc
Background We have demonstrated that brain natriuretic peptide (BNP) is a cardiac
hormone predominantly synthesized in and secreted from the ventricle. We have also …