[HTML][HTML] The SARS-CoV-2 vaccine pipeline: an overview

WH Chen, U Strych, PJ Hotez, ME Bottazzi - Current tropical medicine …, 2020 - Springer
Each current vaccine strategy has distinct advantages and disadvantages. Therefore, it is
paramount that multiple strategies be advanced quickly and then evaluated for safety and …

[HTML][HTML] Targets and strategies for vaccine development against SARS-CoV-2

JA Malik, AH Mulla, T Farooqi, FH Pottoo… - Biomedicine & …, 2021 - Elsevier
Abstract The SARS-CoV-2, previously called a novel coronavirus, that broke out in the
Wuhan city of China caused a significant number of morbidity and mortality in the world. It is …

SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …

[HTML][HTML] An updated review of SARS-CoV-2 vaccines and the importance of effective vaccination programs in pandemic times

C García-Montero, O Fraile-Martínez, C Bravo… - Vaccines, 2021 - mdpi.com
Since the worldwide COVID-19 pandemic was declared a year ago, the search for vaccines
has become the top priority in order to restore normalcy after 2.5 million deaths worldwide …

[HTML][HTML] The 2020 pandemic: current SARS-CoV-2 vaccine development

SO Alturki, SO Alturki, J Connors, G Cusimano… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses are enveloped viruses with a positive-sense single-stranded RNA genome
infecting animals and humans. Coronaviruses have been described more than 70 years ago …

[HTML][HTML] Progress and pitfalls in the quest for effective SARS-CoV-2 (COVID-19) vaccines

KL Flanagan, E Best, NW Crawford, M Giles… - Frontiers in …, 2020 - frontiersin.org
There are currently around 200 SARS-CoV-2 candidate vaccines in preclinical and clinical
trials throughout the world. The various candidates employ a range of vaccine strategies …

[HTML][HTML] Efforts at COVID-19 vaccine development: challenges and successes

A Haque, AB Pant - Vaccines, 2020 - mdpi.com
The rapid spread of SARS-CoV-2, the new coronavirus (CoV), throughout the globe poses a
daunting public health emergency. Different preventive efforts have been undertaken in …

[HTML][HTML] Current clinical trials protocols and the global effort for immunization against SARS-CoV-2

GNA Rego, MP Nucci, AH Alves, FA Oliveira, LC Marti… - Vaccines, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is the biggest health challenge of the 21st century,
affecting millions of people globally. The outbreak of severe acute respiratory syndrome …

SARS-CoV-2 vaccine development: current status

GA Poland, IG Ovsyannikova, SN Crooke… - Mayo Clinic …, 2020 - Elsevier
In the midst of the severe acute respiratory syndrome coronavirus 2 pandemic and its
attendant morbidity and mortality, safe and efficacious vaccines are needed that induce …

[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2

SH Hodgson, K Mansatta, G Mallett, V Harris… - The lancet infectious …, 2021 - thelancet.com
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …