White adipose tissue and liver are important angiotensinogen (AGT) production sites. Until
now, plasma AGT was considered to be a reflection of hepatic production. Because plasma …

Background The adipose tissue renin–angiotensin system (RAS) has been implicated in the
pathophysiology of obesity and dysfunction of adipose tissue. However, neither regulation of …

Synthesis of angiotensin II (ANG II) has recently been described in adipose cells and has
been linked to regulation of adiposity. Angiotensinogen (AGT), the substrate from which …

Previous studies demonstrated that overexpression of angiotensinogen (AGT) in adipose
tissue increased blood pressure. However, the contribution of endogenous AGT in …

Adipose tissue is an important source of angiotensinogen (AGT). Recent evidence shows
that a local renin–angiotensinogen system (RAS) is present in human adipose tissue and …

Adipose tissue represents an important source of angiotensinogen (AGT). We investigated
the effect of obesity induced by a high-fat diet on the expression of mouse (mAGT) and …

We investigated angiotensinogen (AGT) expression in adipose tissue and liver of Zucker
rats during the onset of obesity. The developmental pattern of AGT expression (protein and …

Objective—This study determined whether angiotensinogen (AGT) has angiotensin II–
independent effects using multiple genetic and pharmacological manipulations. Approach …

In addition to the well-defined contribution of the liver, adipose tissue has been recognized
as an important source of angiotensinogen (AGT). The purpose of this study was to define …

White adipose tissue is known to contain the components of the renin-angiotensin system,
which gives rise to angiotensin II from angiotensinogen (AGT). Recent evidence obtained in …