Anthropological studies demonstrate that periodontitis has relatively recent roots, with a
substantial increase in the incidence of generalized periodontitis in post-modern Man. 1 …

This commentary provides background, historical context, and a critical assessment of the
concept that microbial dysbiosis drives the pathogenesis of periodontal diseases. It is long …

This review discusses polymicrobial interactions with the host in both health and disease. As
our ability to identify specific bacterial clonal types, with respect to their abundance and …

The human body supports the growth of a wide array of microbial communities in various
niches such as the oral cavity, gastro-intestinal and urogenital tracts, and on the surface of …

One of the hallmark features of destructive periodontal disease, well documented over the
last 50 y, is a change to the quantitative and qualitative composition of the associated …

The landscape in dentistry is changing as emerging studies continue to reveal that
periodontal health impacts systemic health, and vice versa. Population studies, clinical …

In the mid-1960s the microbial aetiology of periodontal diseases was introduced based on
classical experimental gingivitis studies. Since then, numerous studies have addressed the …

Humans have co-evolved with microorganisms, and both exist in a symbiotic or mutualistic
relationship. We are colonised by a diverse, resident microbiota, which develop into …

In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Periodontitis is driven by disproportionate host inflammatory immune responses induced by
an imbalance in the composition of oral bacteria; this instigates microbial dysbiosis, along …