Background Diversified etiology of lower respiratory tract infection renders diagnosis
challenging. The mainstay microbial culture is time-consuming and constrained by variable …

This review provides an in-depth discussion of the development, principles and utility of
nanopore sequencing technology and its diverse applications in the identification of various …

Respiratory tract infection (RTI) remains a significant cause of morbidity and mortality across
the globe. The optimal management of RTI relies upon timely pathogen identification via …

Background Nanopore metagenomics has been used for infectious disease diagnosis for
bacterial pathogens. However, this technology currently lacks comprehensive performance …

The gold standard for confirming bacterial infections is culture-positive, which has a long
sample-to-result turnaround time and poor sensitivity for unculturable and fastidious …

Objective To evaluate the value of nanopore targeted sequencing in diagnosing pneumonia
pathogens. Methods This large-scale multicentre prospective study performed in 8 hospitals …

Objectives Lower respiratory tract infections (LRTIs) are one of the causes of mortality
among infectious diseases. Microbial cultures commonly used in clinical practice are time …

The rapid and effective identification of pathogens in patients with pulmonary infections has
posed a persistent challenge in medicine, with conventional microbiological tests (CMTs) …

Background: According to WHO, lower respiratory tract infections (LRTI) are the deadliest
communicable disease globally, causing 3.2 million deaths annually. Culture is the gold …

Infectious diseases are major threats to human health and lead to a serious public health
burden. The emergence of new pathogens and the mutation of known pathogens challenge …