Next-generation sequencing is rapidly finding footholds in numerous microbiological fields,
including infectious disease diagnostics. Here, we describe a molecular inversion probe …

Next-generation sequencing has evolved as a powerful tool, with applications that extend
from diagnosis to public health surveillance and outbreak investigations. Short-read …

Whole-genome sequencing has become the method of choice for bacterial outbreak
investigation, with most clinical and public health laboratories currently routinely using short …

Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …

Oxford Nanopore long-read sequencing offers advantages over Illumina short reads for the
identification and characterization of bacterial pathogens for outbreak detection and …

Metagenomic sequencing with the Oxford Nanopore MinION sequencer offers potential for
point-of-care testing of infectious diseases in clinical settings. To improve cost-effectiveness …

To the Editor, Next generation sequencing (NGS) technologies have previously been out of
reach for most front-line diagnostic microbiology laboratories due to high costs, significant …

Due to recent improvements, Nanopore sequencing has become a promising method for
experiments relying on amplicon sequencing. We describe a flexible workflow to generate …

Amplicon sequencing of the 16S rRNA gene is commonly used for the identification of
bacterial isolates in diagnostic laboratories and mostly relies on the Sanger sequencing …

Abstract The MinION sequencer (Oxford Nanopore Technologies) is a paradigm shifting
device allowing rapid, real time long read sequencing of nucleic acids. Yet external …