Immunological mechanisms in the pathogenesis of diabetic retinopathy

AP Adamis, AJ Berman - Seminars in immunopathology, 2008 - Springer
There is an accumulating body of evidence that immunological mechanisms play a
prominent role in the pathogenesis of diabetic retinopathy (DR), which is characterized by …

The role of inflammation in diabetic retinopathy

JV Forrester, L Kuffova, M Delibegovic - Frontiers in immunology, 2020 - frontiersin.org
Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

The role of inflammation in diabetic eye disease

M Mesquida, F Drawnel, S Fauser - Seminars in Immunopathology, 2019 - Springer
Mounting evidence suggests that immunological mechanisms play a fundamental role in the
pathogenesis of diabetic retinopathy (DR) and diabetic macular edema (DME). Upregulation …

[HTML][HTML] Angiogenic factors and cytokines in diabetic retinopathy

SF Abcouwer - Journal of clinical & cellular immunology, 2013 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR) is a sight-threatening complication of both type-1 and type-2
diabetes. The recent success of treatments inhibiting the function of vascular endothelial …

Inflammation in diabetic retinopathy

J Tang, TS Kern - Progress in retinal and eye research, 2011 - Elsevier
Diabetes causes a number of metabolic and physiologic abnormalities in the retina, but
which of these abnormalities contribute to recognized features of diabetic retinopathy (DR) is …

Role of inflammatory cells in pathophysiology and management of diabetic retinopathy

E Kovoor, SK Chauhan, A Hajrasouliha - Survey of ophthalmology, 2022 - Elsevier
Diabetic retinopathy (DR) is a sight-threatening complication of diabetes mellitus. Several
inflammatory cells and proteins, including macrophages and microglia, cytokines, and …

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

L Tang, GT Xu, JF Zhang - Neural regeneration research, 2023 - journals.lww.com
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease,
is the leading cause of visual impairment in diabetic patients. Many clinical features …

Anti-inflammatory therapy for diabetic retinopathy

W Zhang, H Liu, M Rojas, RW Caldwell… - Immunotherapy, 2011 - Taylor & Francis
Diabetic retinopathy (DR) is one of the most common complications of diabetes. This
devastating disease is a leading cause of blindness in people of working age in …

Inflammation and pharmacological treatment in diabetic retinopathy

S Kaštelan, M Tomić… - Mediators of …, 2013 - Wiley Online Library
Diabetic retinopathy (DR), the most common microvascular complication of diabetes
mellitus, is estimated to be the leading cause of new blindness in the working population of …

Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy

D Gologorsky, A Thanos, D Vavvas - Mediators of inflammation, 2012 - Wiley Online Library
The global prevalence of diabetes is estimated to be 336 million people, with diabetic
complications contributing to significant worldwide morbidity and mortality. Diabetic …