SD Koukoui, A Chaudhuri - Brain research reviews, 2007 - Elsevier
Fragile X syndrome (FXS) is a leading cause of inherited mental retardation. In the vast majority of cases, this X-linked disorder is due to a CGG expansion in the 5′ untranslated …
SM Till, LS Wijetunge, VG Seidel… - Human molecular …, 2012 - academic.oup.com
Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and results from the loss of the fragile X mental retardation protein (FMRP). Many fragile X …
CM Spencer, E Serysheva… - Human molecular …, 2006 - academic.oup.com
Individuals affected by Fragile X syndrome (FXS) experience cognitive impairment, hyperactivity, attention deficits, social anxiety and autistic-like behaviors. FXS results from …
DAR Zorio, CM Jackson, Y Liu… - Journal of …, 2017 - Wiley Online Library
The fragile X mental retardation protein (FMRP) plays an important role in normal brain development. Absence of FMRP results in abnormal neuronal morphologies in a selected …
AR Santos, AK Kanellopoulos, C Bagni - Learning & memory, 2014 - learnmem.cshlp.org
The Fragile X syndrome (FXS) is the most frequent form of inherited mental disability and is considered a monogenic cause of autism spectrum disorder. FXS is caused by a triplet …
Fragile X Syndrome (FXS) is the most common single gene cause of inherited mental impairment, and cognitive deficits can range from simple learning disabilities to mental …
V Mercaldo, G Descalzi, M Zhuo - Molecules and cells, 2009 - Springer
Fragile X syndrome (FXS) is caused by a lack of the fragile X mental retardation protein (FMRP) due to silencing of the Fmr1 gene. As an RNA binding protein, FMRP is thought to …
AA Lightbody, AL Reiss - Developmental disabilities research …, 2009 - Wiley Online Library
Fragile X syndrome (FraX) remains the most common inherited cause of intellectual disability and provides a valuable model for studying gene‐brain‐behavior relationships …
Fragile X syndrome is a neurodevelopmental disorder that is caused by the silencing of a single gene on the X chromosome, the fragile X mental retardation 1 (FMR1) gene. Affected …