Human eggs frequently contain an incorrect number of chromosomes, a condition termed
aneuploidy. Aneuploidy affects∼ 10–25% of eggs in women in their early 30s, and more …

Objectives: Correlations between parental age, aneuploidy in germ cells and recent findings
on aetiological factors in mammalian trisomy formation are reviewed. Methods: Data from …

ABSTRACT BACKGROUND The unbalanced transmission of chromosomes in human
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …

One of the main causes of pregnancy failure and fetus abortion is oocyte aneuploidy, which
is increased with maternal aging. Numerous possible causes of oocyte aneuploidy in aged …

The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for
infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than …

The post-reproductive phase or menopause in females is triggered by a physiological timer
that depends on a threshold of follicle number in the ovary. Curiously, reproductive …

It is well established that maternal age is associated with a rapid decline in the production of
healthy and high-quality oocytes resulting in reduced fertility in women older than 35 years …

Aneuploidy in human eggs is the leading cause of pregnancy loss and Down's syndrome.
Aneuploid eggs result from chromosome segregation errors when an egg develops from a …

Chromosome segregation errors in oocytes lead to the production of aneuploid eggs, which
are the leading cause of pregnancy loss and of several congenital diseases such as Down …

Aneuploidy is the most commonly occurring type of chromosome abnormality and the most
significant clinically. It arises mostly due to segregation errors taking place during female …