[HTML][HTML] Targeting multiple signal transduction pathways of SARS-CoV-2: Approaches to COVID-19 therapeutic candidates

S Fakhri, Z Nouri, SZ Moradi, EK Akkol, S Piri… - Molecules, 2021 - mdpi.com
Due to the complicated pathogenic pathways of coronavirus disease 2019 (COVID-19),
related medicinal therapies have remained a clinical challenge. COVID-19 highlights the …

[HTML][HTML] Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronaviruses

Z Shen, A Halberg, JY Fong, J Guo, G Song, B Louie… - Scientific Reports, 2022 - nature.com
COVID-19, first reported in late 2019, is an ongoing pandemic that has been causing
devastation across the globe. Although there are multiple vaccines that can prevent severe …

[HTML][HTML] Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

Tackling SARS-CoV-2: proposed targets and repurposed drugs

S Joshi, M Joshi, MS Degani - Future medicinal chemistry, 2020 - Future Science
The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in
February 2020, has currently infected more than 6 million people with fatalities near 371,000 …

[HTML][HTML] Advances in pathogenesis, progression, potential targets and targeted therapeutic strategies in SARS-CoV-2-Induced COVID-19

H Zhou, WJ Ni, W Huang, Z Wang, M Cai… - Frontiers in …, 2022 - frontiersin.org
As the new year of 2020 approaches, an acute respiratory disease quietly caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus …

[HTML][HTML] Pathophysiology and potential therapeutic candidates for COVID-19: a poorly understood arena

A Samaddar, M Grover, VL Nag - Frontiers in pharmacology, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19), an acute onset pneumonia caused by a novel
Betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged …

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …

[HTML][HTML] Coronavirus infection-associated cell death signaling and potential therapeutic targets

R Yapasert, P Khaw-On, R Banjerdpongchai - Molecules, 2021 - mdpi.com
COVID-19 is the name of the disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection that occurred in 2019. The virus–host-specific …

Recent advances in potential drug therapies combating COVID-19 and related coronaviruses-A perspective

SH Nile, A Nile, S Jalde, G Kai - Food and Chemical Toxicology, 2021 - Elsevier
Coronaviruses (CoVs) are a large family of viruses responsible for the severe
pathophysiological effects on human health. The most severe outbreak includes Severe …

Essential functional molecules associated with SARS-CoV-2 infection: Potential therapeutic targets for COVID-19

K Rajarshi, R Khan, MK Singh, T Ranjan, S Ray, S Ray - Gene, 2021 - Elsevier
The whole world is still suffering substantially from the coronavirus disease 2019 (COVID-
19) outbreak. Several protein-based molecules that are associated with the Severe acute …