A novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike protein
Y Chen, S Lu, H Jia, Y Deng, J Zhou… - Emerging microbes & …, 2017 - Taylor & Francis
Middle East respiratory syndrome coronavirus (MERS-CoV) has caused fatal infections,
some through hospital-acquired transmission, in affected regions since its emergence in …
some through hospital-acquired transmission, in affected regions since its emergence in …
[HTML][HTML] A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses …
An emerging respiratory infectious disease with high mortality, Middle East respiratory
syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in …
syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was first reported in …
Ultrapotent human neutralizing antibody repertoires against Middle East respiratory syndrome coronavirus from a recovered patient
P Niu, S Zhang, P Zhou, B Huang… - The Journal of …, 2018 - academic.oup.com
Abstract Background The Middle East respiratory syndrome coronavirus (MERS-CoV)
causes severe respiratory infection with a high (~ 35%) mortality rate. Neutralizing …
causes severe respiratory infection with a high (~ 35%) mortality rate. Neutralizing …
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein
L Jiang, N Wang, T Zuo, X Shi, KMV Poon… - Science translational …, 2014 - science.org
The recently identified Middle East respiratory syndrome coronavirus (MERS-CoV) causes
severe and fatal acute respiratory illness in humans. However, no prophylactic and …
severe and fatal acute respiratory illness in humans. However, no prophylactic and …
[HTML][HTML] Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
S Zhang, P Zhou, P Wang, Y Li, L Jiang, W Jia, H Wang… - Cell reports, 2018 - cell.com
The major mechanism of antibody-mediated neutralization of the Middle East respiratory
syndrome coronavirus (MERS-CoV) involves competition with the cellular receptor …
syndrome coronavirus (MERS-CoV) involves competition with the cellular receptor …
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies
T Ying, L Du, TW Ju, P Prabakaran, CCY Lau… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT The recently discovered Middle East respiratory syndrome coronavirus (MERS-
CoV) continues to infect humans, with high mortality. Specific, highly effective therapeutics …
CoV) continues to infect humans, with high mortality. Specific, highly effective therapeutics …
[HTML][HTML] Combining a fusion inhibitory peptide targeting the MERS-CoV S2 protein HR1 domain and a neutralizing antibody specific for the S1 protein receptor-binding …
Middle East respiratory syndrome coronavirus (MERS-CoV) has continuously posed a threat
to public health worldwide, yet no therapeutics or vaccines are currently available to prevent …
to public health worldwide, yet no therapeutics or vaccines are currently available to prevent …
[HTML][HTML] A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
Y Li, Y Wan, P Liu, J Zhao, G Lu, J Qi, Q Wang, X Lu… - Cell research, 2015 - nature.com
Abstract The newly-emerging Middle East respiratory syndrome coronavirus (MERS-CoV)
can cause severe and fatal acute respiratory disease in humans. Despite global efforts, the …
can cause severe and fatal acute respiratory disease in humans. Despite global efforts, the …
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike …
L Du, G Zhao, Y Yang, H Qiu, L Wang, Z Kou… - Journal of …, 2014 - Am Soc Microbiol
Prophylactic and therapeutic strategies are urgently needed to combat infections caused by
the newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we …
the newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV). Here, we …
Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus
J Tang, N Zhang, X Tao, G Zhao, Y Guo… - Human vaccines & …, 2015 - Taylor & Francis
Middle East respiratory syndrome (MERS) is an emerging infectious disease caused by
MERS coronavirus (MERS-CoV). The continuous increase of MERS cases has posed a …
MERS coronavirus (MERS-CoV). The continuous increase of MERS cases has posed a …
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