Objective Adults with established diagnoses of serious mental illness (bipolar disorder and
schizophrenia) exhibit structural brain abnormalities, yet less is known about how such …

Importance Structural brain abnormalities are prominent in psychotic disorders, including
schizophrenia. However, it is unclear when aberrations emerge in the disease process and …

Background The evaluation of child and adolescent offspring of patients with schizophrenia
(SzO) or bipolar disorder (BpO) may help understand changes taking place in the brain in …

Objective There is increasing support toward the notion that schizophrenia and bipolar
disorder share neurodevelopmental underpinnings, although areas of divergence remain …

Objective: Psychiatric symptomatology during childhood predicts persistent mental illness
later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the …

Objective In both children and adults, psychiatric illness is associated with structural brain
alterations, particularly in the prefrontal cortex (PFC). However, most studies compare gray …

Background Bipolar disorder (BD) with psychotic symptoms is a specific phenotype that
presents greater risk of relapse and worse outcomes than nonpsychotic BD, however, the …

OBJECTIVE: The objective of the present study is to replicate findings in first-episode
psychosis reporting a smaller volume in brain structures in a population with adolescent …

Background Gray matter morphometry studies have lent seminal insights into the etiology of
mental illness. Existing research has primarily focused on adults and then, typically on a …

Background. Brain morphometry in children and adolescents with first-episode psychosis
offer a unique opportunity for pathogenetic investigations. Methods. We compared high …