[HTML][HTML] How does SARS-CoV-2 targets the elderly patients? A review on potential mechanisms increasing disease severity

A Smorenberg, EJG Peters, PLA van Daele… - European Journal of …, 2021 - Elsevier
Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest …

COVID-19: a comprehensive review on cardiovascular alterations, immunity, and therapeutics in older adults

J Rivera-Torres, N Giron, E San Jose - Journal of Clinical Medicine, 2023 - mdpi.com
Here, we present a review focusing on three relevant issues related to COVID-19 and its
impact in older adults (60 years and older). SARS-CoV-2 infection starts in the respiratory …

[HTML][HTML] Caring for older adults during the COVID-19 pandemic

V Prendki, G Tiseo, M Falcone - Clinical Microbiology and Infection, 2022 - Elsevier
Background Elderly patients represent a high-risk group with increased risk of death from
COVID-19. Despite the number of published studies, several unmet needs in care for older …

SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

J Nikolich-Zugich, KS Knox, CT Rios, B Natt… - Geroscience, 2020 - Springer
Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

Comorbidities and increased mortality of COVID-19 among the elderly: A systematic review

A Péterfi, Á Mészáros, Z Szarvas, M Pénzes… - Physiology …, 2022 - akjournals.com
Purpose The purpose of current review is to conduct a systematic overview of articles
published between 2019 and 2021 on the relationship of comorbidities and mortality due to …

[HTML][HTML] Why does COVID-19 disproportionately affect older people?

AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …

COVID-19 in older people: a rapid clinical review

FE Lithander, S Neumann, E Tenison, K Lloyd… - Age and …, 2020 - academic.oup.com
Introduction the COVID-19 pandemic poses a high risk to older people. The aim of this
article is to provide a rapid overview of the COVID-19 literature, with a specific focus on older …

COVID-19 clinical features and outcomes in elderly patients during six pandemic waves

RM Fericean, O Rosca, C Citu, D Manolescu… - Journal of Clinical …, 2022 - mdpi.com
Many elderly patients with severe SARS-CoV-2 infections and COVID-19 infections are
admitted to intensive care units. Age was previously identified as an independent risk factor …

Clinical features of SARS-CoV-2 infection in older adults

F Remelli, S Volpato… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
In April 2020, the SARS-CoV-2 (COVID-19) infection was declared a pandemic emergency
by the World Health Organization, 1 and after 2 years, in January 2022, the virus had …

Approach to COVID-19 in older adults and indications for improving the outcomes

C Tana, L Moffa, K Falasca, J Vecchiet, M Tana… - Annals of …, 2023 - Taylor & Francis
Background: COVID-19 continues to present challenges in the care of older adults with
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …