Alternative pre-mRNA splicing is a highly cell type–specific process essential to generating
protein diversity. However, the mechanisms responsible for the establishment and …

Alternative splicing is a highly fine-tuned regulated process and one of the main drivers of
proteomic diversity across eukaryotes. The vast majority of human multi-exon genes is …

Understanding how RNA binding proteins control the splicing code is fundamental to human
biology and disease. Here, we present a comprehensive study to elucidate how …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

It is generally thought that splicing factors regulate alternative splicing through binding to
RNA consensus sequences. In addition to these linear motifs, RNA secondary structure is …

Alternative splicing plays critical roles in differentiation, development, and disease and is a
major source for protein diversity in higher eukaryotes. Analysis of alternative splicing …

Alternative precursor messenger RNA (pre-mRNA) splicing plays a pivotal role in the flow of
genetic information from DNA to proteins by expanding the coding capacity of genomes …

Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In
humans, 90%–95% of multi-exon genes produce alternatively spliced RNA transcripts …

Alternative splicing greatly expands the transcriptomic and proteomic diversities related to
physiological and developmental processes in higher eukaryotes. Splicing of long …

RNA secondary structures have been increasingly recognized to play an important
regulatory role in post-transcriptional gene regulation. We recently showed that RNA G …