Early disruption of the microbiome leading to decreased antioxidant capacity and epigenetic changes: implications for the rise in autism
Currently, 1 out of every 59 children in the United States is diagnosed with autism. While
initial research to find the possible causes for autism were mostly focused on the genome …
initial research to find the possible causes for autism were mostly focused on the genome …
Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes
AM Tartaglione, A Villani, MA Ajmone-Cat… - Translational …, 2022 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a sex-biased neurodevelopmental disorder with
a male to female prevalence of 4: 1, characterized by persistent deficits in social …
a male to female prevalence of 4: 1, characterized by persistent deficits in social …
Beyond infection-Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders
Immune molecules such as cytokines and chemokines and the cells that produce them
within the brain, notably microglia, are critical for normal brain development. This recognition …
within the brain, notably microglia, are critical for normal brain development. This recognition …
From maternal diet to neurodevelopmental disorders: a story of neuroinflammation
M Bordeleau, L Fernandez de Cossio… - Frontiers in Cellular …, 2021 - frontiersin.org
Providing the appropriate quantity and quality of food needed for both the mother's well-
being and the healthy development of the offspring is crucial during pregnancy. However …
being and the healthy development of the offspring is crucial during pregnancy. However …
Gut-to-brain axis in autism spectrum disorders: central role for the microbiome
AD Kraneveld, K Szklany, CGM De Theije… - International review of …, 2016 - Elsevier
Autism spectrum disorders (ASDs) are neurodevelopmental disorders, which occur in early
childhood and persist into adulthood. Although the etiology of these disorders is largely …
childhood and persist into adulthood. Although the etiology of these disorders is largely …
Perinatal stress, brain inflammation and risk of autism-review and proposal
A Angelidou, S Asadi, KD Alysandratos, A Karagkouni… - BMC pediatrics, 2012 - Springer
Abstract Background Autism Spectrum Disorders (ASD) are neurodevelopmental disorders
characterized by varying deficits in social interactions, communication, and learning, as well …
characterized by varying deficits in social interactions, communication, and learning, as well …
The plausibility of maternal toxicant exposure and nutritional status as contributing factors to the risk of autism spectrum disorders
JR Nuttall - Nutritional neuroscience, 2017 - Taylor & Francis
Recent research suggests the maternal environment may be especially important for the risk
of developing autism spectrum disorders (ASD). In particular maternal infections …
of developing autism spectrum disorders (ASD). In particular maternal infections …
Bridging from cells to cognition in autism pathophysiology: biological pathways to defective brain function and plasticity
M Anderson, BS Hooker, M Herbert - … and Biotechnology, 4 (2): 167-176, 2008 - osti.gov
We review evidence to support the model that autism may begin when a maternal
environmental, infectious, or autoantibody insult causes inflammation which increases …
environmental, infectious, or autoantibody insult causes inflammation which increases …
Autonomic nervous system neuroanatomical alterations could provoke and maintain gastrointestinal dysbiosis in autism spectrum disorder (ASD): a novel microbiome …
A Beopoulos, M Gea, A Fasano, F Iris - Nutrients, 2021 - mdpi.com
Dysbiosis secondary to environmental factors, including dietary patterns, antibiotics use,
pollution exposure, and other lifestyle factors, has been associated to many non-infective …
pollution exposure, and other lifestyle factors, has been associated to many non-infective …
Maternal inflammation and its ramifications on fetal neurodevelopment
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …
inflammatory insults has been associated with the onset of neurodevelopmental and …