Risk factors in autism: Thinking outside the brain

L Matelski, J Van de Water - Journal of autoimmunity, 2016 - Elsevier
Autism spectrum disorders (ASD) are complex neurodevelopmental conditions that have
been rising markedly in prevalence for the past 30 years, now thought to affect 1 in 68 in the …

Oxidative stress, maternal diabetes, and autism spectrum disorders

B Carpita, D Muti, L Dell'Osso - Oxidative medicine and cellular …, 2018 - Wiley Online Library
Autism spectrum disorders (ASD) are a group of early‐onset neurodevelopmental conditions
characterized by alterations in brain connectivity with cascading effects on …

[HTML][HTML] Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells

JE Le Belle, J Sperry, A Ngo, Y Ghochani, DR Laks… - Stem cell reports, 2014 - cell.com
A period of mild brain overgrowth with an unknown etiology has been identified as one of
the most common phenotypes in autism. Here, we test the hypothesis that maternal …

Diet-induced dysbiosis of the maternal gut microbiome in early life programming of neurodevelopmental disorders

CM Di Gesù, LM Matz, SA Buffington - Neuroscience research, 2021 - Elsevier
The maternal gut microbiome plays a critical role in fetal and early postnatal development,
shaping fundamental processes including immune maturation and brain development …

[引用][C] Critical role of the maternal immune system in the pathogenesis of autism spectrum disorder

D Ravaccia, T Ghafourian - Biomedicines, 2020 - MDPI

Modeling environmental risk factors of autism in mice induces IBD-related gut microbial dysbiosis and hyperserotonemia

JS Lim, MY Lim, Y Choi, GP Ko - Molecular brain, 2017 - Springer
Autism spectrum disorder (ASD) is a range of neurodevelopmental conditions that are
sharply increasing in prevalence worldwide. Intriguingly, ASD is often accompanied by an …

[HTML][HTML] The microbiota modulates gut physiology and behavioral abnormalities associated with autism

EY Hsiao, SW McBride, S Hsien, G Sharon, ER Hyde… - Cell, 2013 - ncbi.nlm.nih.gov
Although autism spectrum disorder (ASD) is defined by core behavioral impairments,
gastrointestinal (GI) symptoms are commonly reported. Subsets of ASD individuals display …

A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder

MR Buehler - Medical hypotheses, 2011 - Elsevier
Autism, an incurable neurodevelopmental brain disorder, is a complex psychopathology in
which the affected individual cannot effectively self-regulate their sensory inputs toward …

Interaction between maternal immune activation and antibiotic use during pregnancy and child risk of autism spectrum disorder

C Holingue, M Brucato, C Ladd‐Acosta… - Autism …, 2020 - Wiley Online Library
Prenatal exposure to maternal immune activation (MIA) has been implicated as a risk factor
for the development of autism spectrum disorder (ASD), though the conditions under which …

Maternal infection and immune involvement in autism

PH Patterson - Trends in molecular medicine, 2011 - cell.com
Recent studies have highlighted a connection between infection during pregnancy and the
increased risk of autism in the offspring. Parallel studies of cerebral spinal fluid, blood and …
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