[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

An insight into novel therapeutic potentials of taxifolin

Y Liu, X Shi, Y Tian, S Zhai, Y Liu, Z Xiong… - Frontiers in …, 2023 - frontiersin.org
Taxifolin is a flavonoid compound, originally isolated from the bark of Douglas fir trees,
which is often found in foods such as onions and olive oil, and is also used in commercial …

An insight into the health-promoting effects of taxifolin (dihydroquercetin)

C Sunil, B Xu - Phytochemistry, 2019 - Elsevier
Abstract Taxifolin (3, 5, 7, 3, 4-pentahydroxy flavanone or dihydroquercetin) is a flavonoid
commonly found in onion, milk thistle, French maritime pine bark and Douglas fir bark. It is …

Plant flavonoid taxifolin inhibits the growth, migration and invasion of human osteosarcoma cells

X Chen, N Gu, C Xue, BR Li - Molecular medicine …, 2018 - spandidos-publications.com
The aim of the present study was to investigate the anti-cancer effects of the natural plant
flavonoid, taxifolin, on human osteosarcoma cancer cells. Taxifolin was demonstrated to …

Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn

P Yang, F Xu, HF Li, Y Wang, FC Li, MY Shang, GX Liu… - Molecules, 2016 - mdpi.com
Taxifolin is a ubiquitous bioactive constituent of foods and herbs. To thoroughly explore its
metabolism in vivo, an HPLC-ESI-IT-TOF-MSn method combined with specific metabolite …

Taxifolin inhibits breast cancer cells proliferation, migration and invasion by promoting mesenchymal to epithelial transition via β-catenin signaling

J Li, L Hu, T Zhou, X Gong, R Jiang, H Li, G Kuang… - Life sciences, 2019 - Elsevier
Aim To investigate the effects and underlying mechanisms of taxifolin on proliferation,
migration and invasion of highly aggressive breast cancer in vitro and in vivo. Main methods …

[HTML][HTML] The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition in vitro and oncogenesis in nude mice

R Wang, X Zhu, Q Wang, X Li, E Wang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Taxifolin is a natural flavonoid with anti-oxidant and anti-proliferative properties.
In this study, we investigated the stemness-related inhibitory effects of taxifolin in two lung …

Antioxidant activity of taxifolin: an activity–structure relationship

F Topal, M Nar, H Gocer, P Kalin… - Journal of enzyme …, 2016 - Taylor & Francis
Taxifolin is a kind of flavanonol, whose biological ability. The objectives of this study were to
investigate the antioxidants and antiradical activities of taxifolin by using different in vitro …

Comparative Anticancer Potentials of Taxifolin and Quercetin Methylated Derivatives against HCT-116 Cell Lines: Effects of O-Methylation on Taxifolin and Quercetin …

HA Mohammed, SA Almahmoud, ESM El-Ghaly… - ACS …, 2022 - ACS Publications
Six flavonoids present in Pulicaria jaubertii, ie, 7, 3′-di-O-methyltaxifolin (1), 3′-O-
methyltaxifolin (2), 7-O-methyltaxifolin (3), taxifolin (4), 3-O-methylquercetin (5), and …

[HTML][HTML] “Picrosides” from Picrorhiza kurroa as potential anti-carcinogenic agents

D Soni, A Grover - Biomedicine & Pharmacotherapy, 2019 - Elsevier
The steady rise in life expectancy, modern life style and changing environmental conditions
are responsible for increasing incidence of cancer. A number of chemical drugs have been …