An overview of human proteins and genes involved in SARS-CoV-2 infection

Z Jahanafrooz, Z Chen, J Bao, H Li, L Lipworth, X Guo - Gene, 2022 - Elsevier
As of July 2021, the outbreak of coronavirus disease 2019 (COVID-19), caused by SARS-
CoV-2, has led to more than 200 million infections and more than 4.2 million deaths globally …

[PDF][PDF] Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

J Li, M Guo, X Tian, X Wang, X Yang, P Wu, C Liu… - Med, 2021 - cell.com
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a global public health …

[HTML][HTML] Genomic variations in the structural proteins of SARS-CoV-2 and their deleterious impact on pathogenesis: a comparative genomics approach

T Mohammad, A Choudhury, I Habib… - Frontiers in cellular …, 2021 - frontiersin.org
A continual rise in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection
causing coronavirus disease (COVID-19) has become a global threat. The main problem …

An overview of basic molecular biology of SARS-CoV-2 and current COVID-19 prevention strategies

A Das, R Ahmed, S Akhtar, K Begum, S Banu - Gene reports, 2021 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) manifests as extreme acute respiratory
conditions caused by a novel beta coronavirus named severe acute respiratory syndrome …

SARS-CoV-2 infection: molecular mechanisms of severe outcomes to suggest therapeutics

N Hartog, W Faber, A Frisch, J Bauss… - Expert review of …, 2021 - Taylor & Francis
Introduction: The year 2020 was defined by the 29,903 base pairs of RNA that codes for the
SARS-CoV-2 genome. SARS-CoV-2 infects humans to cause COVID-19, spreading from …

[HTML][HTML] Human genetic basis of severe or critical illness in COVID-19

XS Ji, B Chen, B Ze, WH Zhou - Frontiers in cellular and infection …, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has led to considerable morbidity and mortality …

Molecular evolution of SARS-CoV-2 during the COVID-19 pandemic

LD González-Vázquez, M Arenas - Genes, 2023 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced diverse
molecular variants during its recent expansion in humans that caused different …

SARS-CoV-2/COVID-19: viral genomics, epidemiology, vaccines, and therapeutic interventions

M Uddin, F Mustafa, TA Rizvi, T Loney, H Al Suwaidi… - Viruses, 2020 - mdpi.com
The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus that
impacts the lower respiratory tract. The spectrum of symptoms ranges from asymptomatic …

The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Host genetic factors determining COVID-19 susceptibility and severity

TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …